KRASG12C ligand-1
KRASG12C ligand-1 is a PROTAC target protein ligand that can be used to synthesize the PROTAC YN14-H (HY-173250). YN14-H is a PROTAC degrader targeting KRASG12C and has antitumor activity.
For research use only. We do not sell to patients.
- Formula: C36H41F2N7O3
- Molecular Weight:657.75
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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KRas G12C |
Chemical Information
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Molecular Weight 657.75
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Formula C36H41F2N7O3
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SMILES
O=C1N(C2=C(C)C=CN=C2C(C)C)C3=NC(C4=C(C=CC=C4OCC5CCNCC5)F)=C(F)C=C3C(N6[C@@H](C)CN(C(C=C)=O)CC6)=N1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)