2. GPCR/G Protein Neuronal Signaling
  3. mAChR
  4. L 689660 maleate

L 689660 maleate, a cholinomimetic agent, is a selective M1 and M3 muscarinic receptors agonist. L 689660 maleate is a potent M1 muscarinic receptor full agonist in the rat superior cervical ganglion (pEC50 of 7.3). L 689660 maleate is a potent M3 receptors agonist in the guinea-pig ileum myenteric plexus-longitudinal muscle or in trachea (pEC50 of 7.5 and 7.7, respectively).

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L 689660 maleate

L 689660 maleate Chemical Structure

CAS No. : 144860-79-7

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L 689660 maleate Related Antibodies

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Description

L 689660 maleate, a cholinomimetic agent, is a selective M1 and M3 muscarinic receptors agonist. L 689660 maleate is a potent M1 muscarinic receptor full agonist in the rat superior cervical ganglion (pEC50 of 7.3). L 689660 maleate is a potent M3 receptors agonist in the guinea-pig ileum myenteric plexus-longitudinal muscle or in trachea (pEC50 of 7.5 and 7.7, respectively)[1][2].

IC50 & Target[1]

mAChR1

 

mAChR3

 

Molecular Weight

339.77

Formula

C15H18ClN3O4
CAS No.
SMILES

ClC1=CN=CC(C2CN3CCC2CC3)=N1.O=C(/C=C\C(O)=O)O.[x]
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Purity & Documentation
References
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L 689660 maleate Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

L 689660144860-79-7L689660L-689660mAChRMuscarinic acetylcholine receptorM1/M3 Muscarinic Receptors Agonistcholinomimetic agentInhibitorinhibitorinhibit

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