L-Glyceric acid sodium
Based on 1 Customer Validation
L-Glyceric acid sodium is a mainly urinary metabolite accumulating in rare inherited metabolic disease L-glyceric aciduria. L-Glyceric acid sodium can be used to diagnose primary hyperoxaluria type 2 (PH2). L-Glyceric acid sodium excretion to distinguish PH1 from PH2.
For research use only. We do not sell to patients.
- Purity: 99.0%
- CAS No.: 146298-95-5
- Formula: C3H5NaO4
- Molecular Weight:128.06
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
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Human Endogenous Metabolite |
Primary hyperoxaluria type 2 (PH2), also called L-glyceric aciduria. The metabolic defect is due to deficiencies of D-glycerate dehydrogenase and glyoxylate reductase, leading to excretion of L-Glyceric acid, and L-Glyceric acid is the cornerstone for the diagnosis of PH2[1][2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 146298-95-5
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Appearance Solid
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Molecular Weight 128.06
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Formula C3H5NaO4
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Color White to off-white
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SMILES
O=C(O[Na])[C@@H](O)CO
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
H2O : 50 mg/mL (390.44 mM; Need ultrasonic)
DMSO : 10 mg/mL (78.09 mM; ultrasonic and warming and heat to 80°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
[1]. Mohamed S Rashed, et al. Chiral liquid chromatography tandem mass spectrometry in the determination of the configuration of glyceric acid in urine of patients with D-glyceric and L-glyceric acidurias. Biomed Chromatogr. 2002 May;16(3):191-8. [Content Brief]
[2]. Bernd Hoppe, et al. A United States survey on diagnosis, treatment, and outcome of primary hyperoxaluria. Pediatr Nephrol. 2003 Oct;18(10):986-91. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO / H2O | 1 mM | 7.8088 mL | 39.0442 mL | 78.0884 mL | 195.2210 mL |
| 5 mM | 1.5618 mL | 7.8088 mL | 15.6177 mL | 39.0442 mL | |
| 10 mM | 0.7809 mL | 3.9044 mL | 7.8088 mL | 19.5221 mL | |
| 15 mM | 0.5206 mL | 2.6029 mL | 5.2059 mL | 13.0147 mL | |
| 20 mM | 0.3904 mL | 1.9522 mL | 3.9044 mL | 9.7610 mL | |
| 25 mM | 0.3124 mL | 1.5618 mL | 3.1235 mL | 7.8088 mL | |
| 30 mM | 0.2603 mL | 1.3015 mL | 2.6029 mL | 6.5074 mL | |
| 40 mM | 0.1952 mL | 0.9761 mL | 1.9522 mL | 4.8805 mL | |
| 50 mM | 0.1562 mL | 0.7809 mL | 1.5618 mL | 3.9044 mL | |
| 60 mM | 0.1301 mL | 0.6507 mL | 1.3015 mL | 3.2537 mL | |
| H2O | 80 mM | 0.0976 mL | 0.4881 mL | 0.9761 mL | 2.4403 mL |
| 100 mM | 0.0781 mL | 0.3904 mL | 0.7809 mL | 1.9522 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
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