1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. L-Glyceric acid sodium

L-Glyceric acid sodium is a mainly urinary metabolite accumulating in rare inherited metabolic disease L-glyceric aciduria. L-Glyceric acid sodium can be used to diagnose primary hyperoxaluria type 2 (PH2). L-Glyceric acid sodium excretion to distinguish PH1 from PH2.

For research use only. We do not sell to patients.

L-Glyceric acid sodium Chemical Structure

L-Glyceric acid sodium Chemical Structure

CAS No. : 146298-95-5

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5 mg USD 400 In-stock
10 mg USD 680 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

L-Glyceric acid sodium is a mainly urinary metabolite accumulating in rare inherited metabolic disease L-glyceric aciduria. L-Glyceric acid sodium can be used to diagnose primary hyperoxaluria type 2 (PH2). L-Glyceric acid sodium excretion to distinguish PH1 from PH2[1][2].

IC50 & Target[1]

Human Endogenous Metabolite

 

In Vitro

Primary hyperoxaluria type 2 (PH2), also called L-glyceric aciduria. The metabolic defect is due to deficiencies of D-glycerate dehydrogenase and glyoxylate reductase, leading to excretion of L-Glyceric acid, and L-Glyceric acid is the cornerstone for the diagnosis of PH2[1][2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

128.06

Formula

C3H5NaO4

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(O[Na])[C@@H](O)CO

Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 50 mg/mL (390.44 mM; Need ultrasonic)

DMSO : 10 mg/mL (78.09 mM; ultrasonic and warming and heat to 80°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 7.8088 mL 39.0442 mL 78.0884 mL
5 mM 1.5618 mL 7.8088 mL 15.6177 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: ≥99.0%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO / H2O 1 mM 7.8088 mL 39.0442 mL 78.0884 mL 195.2210 mL
5 mM 1.5618 mL 7.8088 mL 15.6177 mL 39.0442 mL
10 mM 0.7809 mL 3.9044 mL 7.8088 mL 19.5221 mL
15 mM 0.5206 mL 2.6029 mL 5.2059 mL 13.0147 mL
20 mM 0.3904 mL 1.9522 mL 3.9044 mL 9.7610 mL
25 mM 0.3124 mL 1.5618 mL 3.1235 mL 7.8088 mL
30 mM 0.2603 mL 1.3015 mL 2.6029 mL 6.5074 mL
40 mM 0.1952 mL 0.9761 mL 1.9522 mL 4.8805 mL
50 mM 0.1562 mL 0.7809 mL 1.5618 mL 3.9044 mL
60 mM 0.1301 mL 0.6507 mL 1.3015 mL 3.2537 mL
H2O 80 mM 0.0976 mL 0.4881 mL 0.9761 mL 2.4403 mL
100 mM 0.0781 mL 0.3904 mL 0.7809 mL 1.9522 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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L-Glyceric acid sodium
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HY-113377A
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