L-Lysine α-oxidase
Based on 1 Customer Validation
L-Lysine α-oxidase is a potent anticancer agent. L-Lysine α-oxidase also a L-amino acid oxidase, deaminates L-lysine with the yield of H2O2, ammonia, and α-keto-ε-aminocaproate. L-Lysine α-oxidase shows cytotoxicity and anticancer activity.
For research use only. We do not sell to patients.
- CAS No.: 70132-14-8
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
L-Lysine α-oxidase shows cytotoxicity for HT29, LS174T, MCF7, SKOV3, PC3, K562 cells[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:6-9 weeks, Female Balb/c nude mice (SKBR3, HCT116, Bro, SKOV3, Alex, T47D, LS174T tumor models)[2]
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Dosage:150 U/kg on day 2 and 75 U/kg on days 4, 6, 8, and 10
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Administration:I.p.; 10 U/ml saline solution
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Result:Caused inhibition of tumor growth with maximal T/C of 49, 12, 51, 35, 54,36, 37% for SKBR3, HCT116, Bro, SKOV3, Alex, T47D, LS174T tumor models, respectively.
1.4.3.14
Chemical Information
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CAS No. 70132-14-8
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Appearance Solid
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Color Off-white to light yellow
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SMILES
[L-Lysine alpha-oxidase]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Data Sheet (268 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
[1]. Lukasheva EV, et al. L-Lysine α-Oxidase: Enzyme with Anticancer Properties. Pharmaceuticals (Basel). 2021 Oct 22;14(11):1070. [Content Brief]
[2]. Pokrovsky VS, et al. Enzymatic properties and anticancer activity of L-lysine α-oxidase from Trichoderma cf. aureoviride Rifai BKMF-4268D. Anticancer Drugs. 2013 Sep;24(8):846-51. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
L-Lysine α-oxidase Related Classifications
HY-P2965 Related Classifications
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