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  4. L-Lysine α-oxidase

L-Lysine α-oxidase is a potent anticancer agent. L-Lysine α-oxidase also a L-amino acid oxidase, deaminates L-lysine with the yield of H2O2, ammonia, and α-keto-ε-aminocaproate. L-Lysine α-oxidase shows cytotoxicity and anticancer activity.

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L-Lysine α-oxidase Chemical Structure

L-Lysine α-oxidase Chemical Structure

CAS No. : 70132-14-8

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L-Lysine α-oxidase Related Antibodies

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Description

L-Lysine α-oxidase is a potent anticancer agent. L-Lysine α-oxidase also a L-amino acid oxidase, deaminates L-lysine with the yield of H2O2, ammonia, and α-keto-ε-aminocaproate. L-Lysine α-oxidase shows cytotoxicity and anticancer activity[1][2].

In Vitro

L-Lysine α-oxidase shows cytotoxicity for HT29, LS174T, MCF7, SKOV3, PC3, K562 cells[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

L-Lysine α-oxidase Related Antibodies
In Vivo

L-Lysine α-oxidase (150 U/kg on day 2 and 75 U/kg on days 4, 6, 8, and 10; i.p.) shows anticancer activity in human tumor models[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: 6-9 weeks, Female Balb/c nude mice (SKBR3, HCT116, Bro, SKOV3, Alex, T47D, LS174T tumor models)[2]
Dosage: 150 U/kg on day 2 and 75 U/kg on days 4, 6, 8, and 10
Administration: I.p.; 10 U/ml saline solution
Result: Caused inhibition of tumor growth with maximal T/C of 49, 12, 51, 35, 54,36, 37% for SKBR3, HCT116, Bro, SKOV3, Alex, T47D, LS174T tumor models, respectively.
CAS No.
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

L-Lysine α-oxidase70132-14-8OtherscytotoxicityanticancerHCT 116LS174TT47D cellsInhibitorinhibitorinhibit

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