Lanicemine-d5 dihydrochloride
Lanicemine-d5 dihydrochloride (AZd6765-d5 dihydrochloride) is the deuterium labeled Lanicemine dihydrochloride (HY-108235A). Lanicemine (AZD6765) dihydrochloride is a low-trapping NMDA channel blocker (Ki of 0.56-2.1 μM for NMDA receptor; IC50s of 4-7 μM and 6.4 μM in CHO and Xenopus oocyte cells, respectively). Antidepressant effects.
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- Formel: C13H11D5Cl2N2
- Molecular Weight:276.22
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Unlabeled Cas 153322-06-6
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Molecular Weight 276.22
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Formel C13H11D5Cl2N2
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SMILES
N[C@H](C1=C([2H])C([2H])=C([2H])C([2H])=C1[2H])CC2=NC=CC=C2.Cl.Cl
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Synonyms
AZD6765-d5 dihydrochloride; ARL 15896AR-d5
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)