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Latozinemab

(Synonyms: AL001)
1 Cited Publications
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Based on 1 publication(s) in Google Scholar

Latozinemab (AL001) is a recombinant human anti-Sortilin monoclonal antibody. Latozinemab effectively binds Sortilin with a high affinity and blocks the interaction between progranulin protein (PGRN) and Sortilin receptor. Latozinemab has the potential for progranulin gene (GRN) mutations causative of Frontotemporal dementia (FTD) (FTD-GRN) research.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

  • Reinheit: 96.03%
  • CAS. Nr.: 2376132-27-1
  • Molecular Weight:146.28 kDa
  • Speicherung:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Latozinemab
  • Experimental Validation Results for Latozinemab
  • Latozinemab Chemical Structure
    Latozinemab Chemical Structure
CAS. Nr.: 2376132-27-1
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[email protected] [email protected]
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Assay Types
  • 1/16

    Human IgG1 kappa

  • 1/16

    Flow cytometric analysis of 1X106 K562 cells with Latozinemab (HY-P99688, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Fluor 488-conjugated AffiniPure Goat Anti-Human IgG H&L (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).

  • Latozinemab Chemical Structure
    1/16
  • Latozinemab
  • Flow cytometric analysis of 1X106 K562 cells with Latozinemab (HY-P99688, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Fluor 488-conjugated AffiniPure Goat Anti-Human IgG H&L (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).