N-Demethyl Mifepristone
N-Demethyl Mifepristone (RU 42633) is an active metabolite of Mifepristone (HY-13683). The affinities of N-Demethyl Mifepristone to the glucocorticoid receptor is 61% compared with 100% for Mifepristone.
For research use only. We do not sell to patients.
- CAS No.: 104004-96-8
- Formula: C28H33NO2
- Molecular Weight:415.57
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HCC1937 | IC50 |
>20 μM
Compound: 2
|
Antiproliferative activity against human HCC1937 cells after 48 hrs by SRB assay
Antiproliferative activity against human HCC1937 cells after 48 hrs by SRB assay
|
[PMID: 29407962] |
| SUM149PT | IC50 |
>20 μM
Compound: 2
|
Antiproliferative activity against human SUM149PT cells after 48 hrs by SRB assay
Antiproliferative activity against human SUM149PT cells after 48 hrs by SRB assay
|
[PMID: 29407962] |
| T47D | IC50 |
0.17 nM
Compound: 2
|
Antagonist activity at progesterone receptor in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity after 48 hrs
Antagonist activity at progesterone receptor in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity after 48 hrs
|
[PMID: 19216549] |
| T47D | IC50 |
0.17 nM
Compound: 11, Desmethylmifepristone
|
Antiprogestagenic activity at progesterone receptor in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity
Antiprogestagenic activity at progesterone receptor in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity
|
[PMID: 20149664] |
Chemical Information
-
CAS No. 104004-96-8
-
Molecular Weight 415.57
-
Formula C28H33NO2
-
SMILES
C[C@@]12[C@](CC[C@@]2(O)C#CC)([H])[C@@]3([H])C([C@@H](C4=CC=C(C=C4)NC)C1)=C5C(CC3)=CC(CC5)=O
-
Synonyms
RU 42633
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
N-Demethyl Mifepristone Related Classifications
HY-W740216 Related Classifications
Powered by Bioz