NH2-Gly-PAB-Exatecan-D-glucuronic acid
NH2-Gly-PAB-Exatecan-D-glucuronic acid (Compound 8) is an intermediate, which reacts with NHS group to form drug-linker conjugate for ADC, Mal-Gly-PAB-Exatecan-D-glucuronic acid (HY-153179).
For research use only. We do not sell to patients.
- CAS No.: 2763252-31-7
- Formula: C40H40FN5O14
- Molecular Weight:833.77
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Drug-Linker Conjugates for ADC Isoforms
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Biological Activity
Description
In Vitro
Mal-Gly-PAB-Exatecan-D-glucuronic acid is used for the synthesis of antibody-drug conjugates (ADCs)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2763252-31-7
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Molecular Weight 833.77
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Formula C40H40FN5O14
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SMILES
NCC(NC(C=C1COC(N[C@@H]2C3=C4C(C(N5C4)=CC([C@](O)(C(OC6)=O)CC)=C6C5=O)=NC7=CC(F)=C(C)C(CC2)=C73)=O)=C(C=C1)O[C@@H]8O[C@@H]([C@H]([C@@H]([C@H]8O)O)O)C(O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)