NH2-Gly-PAB-Exatecan-D-glucuronic acid formic

Cat. No.: HY-160885A Pureté: 99.34%: Fiche technique
COA

SDS
Instruction de manipulation
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NH2-Gly-PAB-Exatecan-D-glucuronic acid formic (Compound 8) is the formic salt form of H2N-Gly-PAB-Exatecan-D-glucuronic acid. H2N-Gly-PAB-Exatecan-D-glucuronic acid formic is an intermediate, which reacts with NHS group to form drug-linker conjugate for ADC, Mal-Gly-PAB-Exatecan-D-glucuronic acid (HY-153179).

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NH2-Gly-PAB-Exatecan-D-glucuronic acid formic Chemical Structure

Size	Stock	Quantité
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	En stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	En stock	Estimated Time of Arrival: December 31
Solid
5 mg	En stock	Estimated Time of Arrival: December 31
10 mg	En stock	Estimated Time of Arrival: December 31
25 mg	En stock	Estimated Time of Arrival: December 31
50 mg	En stock	Estimated Time of Arrival: December 31
100 mg	En stock	Estimated Time of Arrival: December 31
200 mg	Obtenir un devis
500 mg	Obtenir un devis

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Other Forms of NH2-Gly-PAB-Exatecan-D-glucuronic acid formic:

NH2-Gly-PAB-Exatecan-D-glucuronic acid Obtenir un devis

Recommandations en vedette

•Related Screening Libraries:

•Related Small Molecules:

•Related Proteins:

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Description

Masse moléculaire

879.79

Formule

C₄₁H₄₂FN₅O₁₆

Appearance

Solid

Color

White to light yellow

SMILES

NCC(NC(C=C1COC(N[C@@H]2C3=C4C(C(N5C4)=CC([C@](O)(C(OC6)=O)CC)=C6C5=O)=NC7=CC(F)=C(C)C(CC2)=C73)=O)=C(C=C1)O[C@@H]8O[C@@H]([C@H]([C@@H]([C@H]8O)O)O)C(O)=O)=O.OC=O

Livraison

Room temperature in continental US; may vary elsewhere.

Stockage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvant et solubilité

In Vitro:

DMSO : 50 mg/mL (56.83 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.1366 mL	5.6832 mL	11.3663 mL
5 mM	0.2273 mL	1.1366 mL	2.2733 mL
10 mM	0.1137 mL	0.5683 mL	1.1366 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Calculateur de molarité
Calculateur de dilution

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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μL

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Pureté et documentation

Purity: 99.34%

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Fiche technique (277 KB) SDS (252 KB)

COA (265 KB) HNMR (268 KB) RP-HPLC (268 KB) LCMS (101 KB)

Instruction de manipulation (2659 KB)

Références

[1]. DICKGIESSER S, et al., Methods and tools for conjugation to antibodies. WO2023170239.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	1.1366 mL	5.6832 mL	11.3663 mL	28.4159 mL
	5 mM	0.2273 mL	1.1366 mL	2.2733 mL	5.6832 mL
	10 mM	0.1137 mL	0.5683 mL	1.1366 mL	2.8416 mL
	15 mM	0.0758 mL	0.3789 mL	0.7578 mL	1.8944 mL
	20 mM	0.0568 mL	0.2842 mL	0.5683 mL	1.4208 mL
	25 mM	0.0455 mL	0.2273 mL	0.4547 mL	1.1366 mL
	30 mM	0.0379 mL	0.1894 mL	0.3789 mL	0.9472 mL
	40 mM	0.0284 mL	0.1421 mL	0.2842 mL	0.7104 mL
	50 mM	0.0227 mL	0.1137 mL	0.2273 mL	0.5683 mL