Metal Nanoparticles
DMSA Coated Fe2O3 Nanoparticles (Carboxylated ferric oxide nanoparticles) are magnetic nanomaterials with carboxyl (-COOH) groups modified on their surface. These materials typically consist of ferric oxide (Fe2O3) nanoparticles as a core, with carboxyl functional groups introduced to the surface through chemical modification. The carboxylation of the nanoparticle surface increases its negative surface charge, contributing to improved solubility and stability in water. Carboxylated ferric oxide nanoparticles exhibit good biocompatibility, making them suitable for biomedical applications.
PEGylated iron oxide nanoparticles (amino-terminated) are prepared by high-temperature pyrolysis and modified with PEG-amino-terminated oleic acid-modified iron oxide. This modification transforms the nanoparticles from the oil phase to the aqueous phase, thereby broadening their application in the biological field.
Due to their unique physical and chemical properties, noble metal nanoparticles, represented by platinum, gold, silver, and palladium, have been extensively studied by many scientists. Palladium is a noble metal belonging to the platinum group elements. Its elemental form is a silvery-white transition metal, soft in texture and possessing good ductility and malleability. Palladium nanoparticles, due to their unique physical, chemical, and electronic properties, have shown remarkable application potential in multiple fields. PEI surface modification of palladium nanoparticles can significantly improve their dispersibility, stability, and biocompatibility, and facilitate further coupling with other biomolecules or fluorescent molecules.
Due to their unique physical and chemical properties, noble metal nanoparticles, represented by platinum, gold, silver, and palladium, have been extensively studied by many scientists. Palladium is a noble metal belonging to the platinum group elements. Its elemental form is a silvery-white transition metal, soft in texture and possessing good ductility and malleability. Palladium nanoparticles, due to their unique physical, chemical, and electronic properties, have shown remarkable application potential in multiple fields. Surface modification of palladium nanoparticles with sodium citrate can significantly improve their dispersibility, stability, and biocompatibility, and facilitate further coupling with other biomolecules or fluorescent molecules.
Selenium (Se) is an essential trace element for the human body, playing a vital role in various physiological activities. In the body, selenium is bound to selenocysteine, an amino acid used to synthesize several selenoproteins. Selenium is often the active site of these proteins, playing a crucial role in maintaining intracellular redox balance. Chitosan-stabilized selenium nanoparticles (CS-SeNPs) are nanomaterials using the biopolymer chitosan (CS) as a stabilizer. Through electrostatic interactions, chitosan coats the surface of selenium nanoparticles (Se NPs), improving their dispersibility, stability, and biocompatibility. Se NPs themselves are characterized by low toxicity and high bioactivity, and the introduction of chitosan further enhances their functionality and application potential, making them widely recognized in biomedicine, food, and agriculture.
Silver nanoclusters (AgNCs) are ultrasmall nanoparticles composed of several to tens of silver atoms. Their size is close to the Fermi wavelength of electrons, thus exhibiting unique molecular-like properties, such as strong fluorescence. Silver nanoclusters possess small size, low toxicity, excellent photostability, large Stokes shift, and good biocompatibility. Lipoic acid (also known as octylsulfonic acid) acts as a ligand in the synthesis of silver nanoclusters, primarily playing a role in stabilizing and protecting the silver nanoclusters. The ligand binds to silver atoms through its specific chemical structure, forming a stable nanocluster structure and influencing the physicochemical properties of the clusters, such as fluorescence performance, catalytic activity, and biocompatibility. This demonstrates potential application value in various fields such as chemical analysis, biosensing, catalysis, medicine, and bioimaging.
