1. GPCR/G Protein MAPK/ERK Pathway
  2. Ras
  3. pan-KRAS-IN-3

pan-KRAS-IN-3 (Example 84) is a pan-KRAS inhibitor. pan-KRAS-IN-3 can be used for research of cancers. pan-KRAS-IN-3 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

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pan-KRAS-IN-3

pan-KRAS-IN-3 Estructura química

No. CAS : 2875116-29-1

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Descripciòn

pan-KRAS-IN-3 (Example 84) is a pan-KRAS inhibitor. pan-KRAS-IN-3 can be used for research of cancers[1]. pan-KRAS-IN-3 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

IC50 & Target

K-Ras WT

 

Peso molecular

587.63

Fòrmula

C33H32F3N5O2

No. CAS
SMILES

FC1=C(C2=CC(O)=CC3=C2C(C#C)=C(F)C=C3)N=CC4=C1N=C(N=C4N5CCCCCC5)OC[C@@]67N(CCC7)C[C@@H](C6)F

Envío

Room temperature in continental US; may vary elsewhere.

Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Inquiry Information

Nombre del producto:
pan-KRAS-IN-3
Cat. No.:
HY-156555
Cantidad:
MCE Japan Authorized Agent: