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  4. Parsaclisib hydrochloride (Standard)

Parsaclisib hydrochloride (Standard)  (Synonyms: INCB050465 hydrochloride (Standard); IBI-376 hydrochloride (Standard))

Cat. No.: HY-109068AR
Handling Instructions Technical Support

Parsaclisib hydrochloride (Standard) is the analytical standard of Parsaclisib (hydrochloride) (HY-109068A). This product is intended for research and analytical applications. Parsaclisib hydrochloride (INCB050465 hydrochloride) is a potent, selective and orally active inhibitor of PI3Kδ, with an IC50 of 1 nM at 1 mM ATP. Parsaclisib hydrochloride shows approximately 20000-fold selectivity over other PI3K class I isoforms. Parsaclisib hydrochloride can be used for the research of relapsed or refractory B-cell malignancies.

For research use only. We do not sell to patients.

Parsaclisib hydrochloride (Standard)

Parsaclisib hydrochloride (Standard) Chemical Structure

CAS No. : 1995889-48-9

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Information

Parsaclisib hydrochloride (Standard) is the analytical standard of Parsaclisib (hydrochloride) (HY-109068A). This product is intended for research and analytical applications. Parsaclisib hydrochloride (INCB050465 hydrochloride) is a potent, selective and orally active inhibitor of PI3Kδ, with an IC50 of 1 nM at 1 mM ATP. Parsaclisib hydrochloride shows approximately 20000-fold selectivity over other PI3K class I isoforms. Parsaclisib hydrochloride can be used for the research of relapsed or refractory B-cell malignancies.

Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Molecular Weight

469.34

Formula

C20H23Cl2FN6O2
CAS No.
SMILES

CCOC1=C([C@@H](C2)CNC2=O)C(F)=C(Cl)C=C1[C@@H](N3C4=NC=NC(N)=C4C(C)=N3)C.[H]Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Parsaclisib hydrochloride (Standard) Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Parsaclisib hydrochloride (Standard)1995889-48-9INCB050465 hydrochloride (Standard) IBI-376 hydrochloride (Standard)Reference StandardsPI3KPhosphoinositide 3-kinasePI3KδrelapsedrefractoryB-cellmalignanciesInhibitorinhibitorinhibit

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