PD-1/PD-L1-IN-58

Cat. No.: HY-W097223 Pureza: 99.20%: Ficha de datos
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PD-1/PD-L1-IN-58 (compound 2) is a novel inhibitor of PD-1/PD-L1. PD-1/PD-L1-IN-58 selectively binds to PD-L1 over PD-1, with a dissociation rate constant (K_D) value of 77.60 nM. PD-1/PD-L1-IN-58 has oral activity. PD-1/PD-L1-IN-58 can be used in the research of influenza A virus.

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PD-1/PD-L1-IN-58 Estructura química

No. CAS : 135-57-9

Tamaño	Stock	Cantidad
50 g	En stock	Estimated Time of Arrival: December 31
100 g	En stock	Estimated Time of Arrival: December 31
500 g	En stock	Estimated Time of Arrival: December 31
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Descripciòn	PD-1/PD-L1-IN-58 (compound 2) is a novel inhibitor of PD-1/PD-L1. PD-1/PD-L1-IN-58 selectively binds to PD-L1 over PD-1, with a dissociation rate constant (K_D) value of 77.60 nM. PD-1/PD-L1-IN-58 has oral activity. PD-1/PD-L1-IN-58 can be used in the research of influenza A virus^[1].
Peso molecular	456.58
Fòrmula	C₂₆H₂₀N₂O₂S₂
No. CAS	135-57-9
Appearance	Solid
SMILES	O=C(C1=CC=CC=C1)NC2=CC=CC=C2SSC3=CC=CC=C3NC(C4=CC=CC=C4)=O
Envío	Room temperature in continental US; may vary elsewhere.
Almacenamiento	4°C, stored under nitrogen *In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Pureza y Documentación	Purity: 99.20% Select Batch: Ficha de datos (272 KB) SDS (393 KB) COA (258 KB) HNMR (132 KB) RP-HPLC (243 KB) LCMS (327 KB) Instrucciones de manejo (2659 KB)
Referencias	[1]. Yoshiyuki Hirata, et al. Discovery of novel disulfide-containing PD-1/PD-L1 inhibitor with in vivo influenza therapeutic efficacy. Sci Rep [Content Brief]

PD-1/PD-L1-IN-58 Related Classifications

Infection

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
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The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

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Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PD-1/PD-L1-IN-58135-57-9PD-1/PD-L1PD-1/Programmed death-ligand 1oral activityinfluenza A virusInhibitorinhibitorinhibit

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PD-1/PD-L1-IN-58

PD-1/PD-L1-IN-58 Related Antibodies

Recomendaciones destacadas

•Related Screening Libraries:

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PD-1/PD-L1-IN-58 Related Classifications

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