135-57-9
Chemical Structure
PD-1/PD-L1-IN-58
- CAS No.: 135-57-9
- Formula:C26H20N2O2S2
- Molecular Weight:456.58
IUPAC Name: N,N'-(disulfanediylbis(2,1-phenylene))dibenzamide
InChIKey: ZHMIOPLMFZVSHY-UHFFFAOYSA-N
SMILES: O=C(C1=CC=CC=C1)NC2=CC=CC=C2SSC3=CC=CC=C3NC(C4=CC=CC=C4)=O
Biological Activity: PD-1/PD-L1-IN-58 (compound 2) is a novel inhibitor of PD-1/PD-L1. PD-1/PD-L1-IN-58 selectively binds to PD-L1 over PD-1, with a dissociation rate constant (KD) value of 77.60 nM. PD-1/PD-L1-IN-58 has oral activity. PD-1/PD-L1-IN-58 can be used in the research of influenza A virus[1].
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PD-1/PD-L1-IN-58 | 99.20% | PD-1/PD-L1-IN-58 (compound 2) is a novel inhibitor of PD-1/PD-L1. PD-1/PD-L1-IN-58 selectively binds to PD-L1 over PD-1, with a dissociation rate constant (KD) value of 77.60 nM. PD-1/PD-L1-IN-58 has oral activity. PD-1/PD-L1-IN-58 can be used in the research of influenza A virus. | ||||||||||||||||||||
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Keywords