PDGFRα Kinase inhibitor 1 (Standard)
PDGFRα Kinase inhibitor 1 (Standard) is the analytical standard of PDGFRα Kinase inhibitor 1 (HY-111507). This product is intended for research and analytical applications. PDGFRα Kinase inhibitor 1 is a highly selective type II PDGFRα Kinase inhibitor with IC50s of 132 nM and 6115 nM for PDGFRα and PDGFRβ, respectively.
For research use only. We do not sell to patients.
- CAS No.: 2209053-93-8
- Formula: C34H34N8O2
- Molecular Weight:586.69
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
Information
Application
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 2209053-93-8
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Molecular Weight 586.69
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Formula C34H34N8O2
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SMILES
CC(C=CC(NC(C1=CC=C(CN(CCN(C)C)C(C2=CC=CN=C2)=O)C=C1)=O)=C3)=C3NC4=NC=CC(C5=CC=CN=C5)=N4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Wang Q, et al. Discovery of 4-((N-(2-(dimethylamino)ethyl)acrylamido)methyl)-N-(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)benzamide (CHMFL-PDGFR-159) as a highly selective type II PDGFRα kinase inhibitor for PDGFRα driving chronic eosinophilic leukemia. Eur J Med Chem. 2018 Apr 25;150:366-384. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)