Sodium phosphate dibasic dodecahydrate
Based on 1 Customer Validation
Phosphoric acid disodium dodecahydrate is an inorganic compound and food additive. Phosphoric acid disodium dodecahydrate promotes gel formation, improves food texture and thermal properties of materials. Phosphoric acid disodium dodecahydrate induces glomerular calcification. Phosphoric acid disodium dodecahydrate can be used in kidney disease research.
For research use only. We do not sell to patients.
- CAS No.: 10039-32-4
- Formula: Na2HPO4·12H2O
- Molecular Weight:358.14
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Storage:
Store at room temperature, keep dry and cool.
In solvent -80°C, 1 year , -20°C, 6 months
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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HY-Y0332B
Potassium dihydrogen phosphate, AR,99.5%
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HY-W094497
Sodium dihydrogen phosphate monohydrate
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HY-D0227
THAM
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HY-Y0308E
Sodium phosphate dibasic, for cell culture
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HY-B2243D
Anhydrous sodium dihydrogen phosphate, for cell culture
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HY-B2243
Anhydrous sodium dihydrogen phosphate
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HY-B2243B
Anhydrous sodium dihydrogen phosphate, for molecular biology
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HY-Y0308
Disodium phosphate
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HY-Y0308H
Sodium phosphate dibasic, for molecular biology
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HY-B2243A
Anhydrous sodium dihydrogen phosphate, for HPLC
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HY-W094510
Sodium pyrophosphate decahydrate
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HY-Y0332C
Sodium dihydrogen phosphate dihydrate,≥99.0%
Biological Activity
Phosphoric acid disodium dodecahydrate (0.5-1.5 M) induces the gelation of thiolated citrus high-methoxyl pectin (TCHMP)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Male Sprague–Dawley rats (Jcl:SD), 5 weeks old[3]
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Dosage:1, 28, 284, 408 mg/kg
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Administration:Intravenous bolus injection via the tail vein, once daily, for 14 days
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Result:Caused treatment-related proteinuria on days 7 and 13.
Caused a pale kidney appearance.
Caused the deposition of dense basophilic granules in the glomeruli (von Kossa-positive) and a dose-dependent degeneration of the glomerular and parietal epithelium.
Caused podocyte fusion, increased microvilli, abundant debris in Bowman's spaces, and low-density lamellar structures in various parts of the glomerulus.
Showed particles containing phosphorus and calcium mixed with a lamellar structure.
Chemical Information
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CAS No. 10039-32-4
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Appearance <35°C Solid,>35°C Liquid
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Molecular Weight 358.14
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Formula Na2HPO4·12H2O
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Color White to off-white
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SMILES
[Na2HPO4 ?12H2O]
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Synonyms
Disodium hydrogen phosphate dodecahydrate; Disodium phosphate dodecahydrate
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Store at room temperature, keep dry and cool
In solvent -80°C 1 year -20°C 6 months
Solvent & Solubility
H2O : 50 mg/mL (139.61 mM; Need ultrasonic)
DMSO : < 1 mg/mL (insoluble or slightly soluble)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (270 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
[1]. Chen J, et al. The gelation behavior of thiolated citrus high-methoxyl pectin induced by sodium phosphate dibasic dodecahydrate. Carbohydr Polym. 2022;277:118849. [Content Brief]
[2]. Shen Z, et al. Use of cellulose nanofibril (CNF)/silver nanoparticles (AgNPs) composite in salt hydrate phase change material for efficient thermal energy storage. Int J Biol Macromol. 2021 Mar 31;174:402-412. [Content Brief]
[3]. Tsuchiya N, et al. Glomerular calcification induced by bolus injection with dibasic sodium phosphate solution in Sprague-Dawley rats. Toxicol Pathol. 2004 Jul-Aug;32(4):408-12. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 2.7922 mL | 13.9610 mL | 27.9220 mL | 69.8051 mL |
| 5 mM | 0.5584 mL | 2.7922 mL | 5.5844 mL | 13.9610 mL | |
| 10 mM | 0.2792 mL | 1.3961 mL | 2.7922 mL | 6.9805 mL | |
| 15 mM | 0.1861 mL | 0.9307 mL | 1.8615 mL | 4.6537 mL | |
| 20 mM | 0.1396 mL | 0.6981 mL | 1.3961 mL | 3.4903 mL | |
| 25 mM | 0.1117 mL | 0.5584 mL | 1.1169 mL | 2.7922 mL | |
| 30 mM | 0.0931 mL | 0.4654 mL | 0.9307 mL | 2.3268 mL | |
| 40 mM | 0.0698 mL | 0.3490 mL | 0.6981 mL | 1.7451 mL | |
| 50 mM | 0.0558 mL | 0.2792 mL | 0.5584 mL | 1.3961 mL | |
| 60 mM | 0.0465 mL | 0.2327 mL | 0.4654 mL | 1.1634 mL | |
| 80 mM | 0.0349 mL | 0.1745 mL | 0.3490 mL | 0.8726 mL | |
| 100 mM | 0.0279 mL | 0.1396 mL | 0.2792 mL | 0.6981 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Sodium phosphate dibasic dodecahydrate Related Classifications
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