Disodium phosphate
Based on 1 Customer Validation
Disodium phosphate is commonly used as a food additive, buffer and laboratory reagent. Disodium phosphate has unique chemical properties that make it an important ingredient in the manufacture of fertilizers, detergents and water treatment products. Additionally, it is used in various medical applications such as osmotic laxatives and electrolyte replacement solutions.
For research use only. We do not sell to patients.
- Purity: 99.1%
- CAS No.: 7558-79-4
- Formula: Na2HPO4
- Molecular Weight:141.96
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Storage:
Store at room temperature, keep dry and cool.
In solvent -80°C, 1 year , -20°C, 6 months
Biological Activity
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HEK293 | EC50 |
32 μM
Compound: 24203
|
Substrate uptake by the Sodium-Dependent Phosphate Transport Protein 2A (NPT2a, SLC34A1) as assessed by the fluorescent FLIPR membrane potential dye in HEK-293 JumpIN-SLC34A1 cells
Substrate uptake by the Sodium-Dependent Phosphate Transport Protein 2A (NPT2a, SLC34A1) as assessed by the fluorescent FLIPR membrane potential dye in HEK-293 JumpIN-SLC34A1 cells
|
10.5281/zenodo.7355196 |
Disodium phosphate is also known as Na2HPO4 to adjust pH of liquid. Disodium phosphate can be used as an excipient, such as buffer, chelating agent. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs[1][2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 7558-79-4
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Appearance Solid
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Molecular Weight 141.96
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Formula Na2HPO4
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Color White to off-white
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SMILES
[Na2HPO4]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Store at room temperature, keep dry and cool
In solvent -80°C 1 year -20°C 6 months
Solvent & Solubility
H2O : 100 mg/mL (704.42 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (270 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 7.0442 mL | 35.2212 mL | 70.4424 mL | 176.1059 mL |
| 5 mM | 1.4088 mL | 7.0442 mL | 14.0885 mL | 35.2212 mL | |
| 10 mM | 0.7044 mL | 3.5221 mL | 7.0442 mL | 17.6106 mL | |
| 15 mM | 0.4696 mL | 2.3481 mL | 4.6962 mL | 11.7404 mL | |
| 20 mM | 0.3522 mL | 1.7611 mL | 3.5221 mL | 8.8053 mL | |
| 25 mM | 0.2818 mL | 1.4088 mL | 2.8177 mL | 7.0442 mL | |
| 30 mM | 0.2348 mL | 1.1740 mL | 2.3481 mL | 5.8702 mL | |
| 40 mM | 0.1761 mL | 0.8805 mL | 1.7611 mL | 4.4026 mL | |
| 50 mM | 0.1409 mL | 0.7044 mL | 1.4088 mL | 3.5221 mL | |
| 60 mM | 0.1174 mL | 0.5870 mL | 1.1740 mL | 2.9351 mL | |
| 80 mM | 0.0881 mL | 0.4403 mL | 0.8805 mL | 2.2013 mL | |
| 100 mM | 0.0704 mL | 0.3522 mL | 0.7044 mL | 1.7611 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.