1. GPCR/G Protein
    Apoptosis
  2. P2Y Receptor
    Apoptosis
  3. PSB 0474

PSB 0474 

Cat. No.: HY-108654
Handling Instructions

PSB 0474 (3-phenacyl-UDP) is a selective and potent P2Y6 receptor agonist with an EC50 of 70 nM. PSB 0474 inhibits cell proliferation, increases NO release in astrocytes and microglia cells. PSB 0474 induces astrocytes apoptosis.

For research use only. We do not sell to patients.

PSB 0474 Chemical Structure

PSB 0474 Chemical Structure

CAS No. : 917567-60-3

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Description

PSB 0474 (3-phenacyl-UDP) is a selective and potent P2Y6 receptor agonist with an EC50 of 70 nM[1]. PSB 0474 inhibits cell proliferation, increases NO release in astrocytes and microglia cells. PSB 0474 induces astrocytes apoptosis[2].

IC50 & Target

IC50: 70 nM (P2Y6)[1]

Molecular Weight

522.29

Formula

C17H20N2O13P2

CAS No.
SMILES

O[[email protected]]([[email protected]@H]1O)[[email protected]@](N(C=CC2=O)C(N2CC(C3=CC=CC=C3)=O)=O)([H])O[[email protected]@H]1CO[P](O[P](O)(O)=O)(O)=O

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Product Name:
PSB 0474
Cat. No.:
HY-108654
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