Whole exome sequencing identifies the TNNI3K gene as a cause of familial conduction system disease and congenital junctional ectopic tachycardia

  • Int J Cardiol. 2015 Apr 15:185:114-6. doi: 10.1016/j.ijcard.2015.03.130.
Yanwei Xi  1 ,  Christina Honeywell  2 ,  Dapeng Zhang  3 ,  Jeremy Schwartzentruber  4 ,  Chandree L Beaulieu  2 ,  Martine Tetreault  5 ,  Taila Hartley  2 ,  Jennifer Marton  6 ,  Silvia M Vidal  6 ,  Jacek Majewski  5 ,  L Aravind  3 ,  Care4Rare Canada Consortium ,  Michael Gollob  7 ,  Kym M Boycott  8 ,  Robert M Gow  9
Affiliations
  • 1. Children's Hospital of Eastern Ontario Research Institute, University of Ottawa, Ottawa, Ontario, Canada.
  • 2. Department of Pediatrics, Children's Hospital of Eastern Ontario, Ottawa, Ontario, Canada.
  • 3. National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD, USA.
  • 4. McGill University and Genome Quebec Innovation Centre, Montreal, Quebec, Canada.
  • 5. McGill University and Genome Quebec Innovation Centre, Montreal, Quebec, Canada; Department of Human Genetics, McGill University, Montreal, Quebec, Canada.
  • 6. Department of Human Genetics, McGill University, Montreal, Quebec, Canada.
  • 7. Toronto General Hospital, Department of Cardiology, University of Toronto, Toronto, Ontario, Canada.
  • 8. Children's Hospital of Eastern Ontario Research Institute, University of Ottawa, Ottawa, Ontario, Canada; Department of Pediatrics, Children's Hospital of Eastern Ontario, Ottawa, Ontario, Canada. Electronic address: [email protected].
  • 9. Department of Pediatrics, Children's Hospital of Eastern Ontario, Ottawa, Ontario, Canada. Electronic address: [email protected].
PMID: 25791106 DOI: 10.1016/j.ijcard.2015.03.130
Keywords
Exome sequencing; Junctional ectopic tachycardia; TNNI3K.