New alkaloids from the leaves of Evodia rutaecarpa

  • Nat Prod Res. 2016 Oct;30(19):2154-9. doi: 10.1080/14786419.2016.1146888.
Xiao Xia  1 ,  Jian-Guang Luo  1 ,  Rui-Huan Liu  1 ,  Ming-Hua Yang  1 ,  Ling-Yi Kong  1
Affiliations
  • 1. a State Key Laboratory of Natural Medicines, Department of Natural Medicinal Chemistry , China Pharmaceutical University , Nanjing , People's Republic of China.
PMID: 26923350 DOI: 10.1080/14786419.2016.1146888
Abstract

One new indole alkaloid (1) and one new indole alkaloidal glycoside (2), together with nine known Alkaloids (3-11), were isolated from the leaves of Evodia rutaecarpa. Their structures were determined on the basis of spectroscopic and chemical methods. Compound 4 exhibited potent activity against Pseudomonas aeruginosa with an MIC value of 7.13 μg/ml.

Keywords
Evodia rutaecarpa; Rutaceae; antibacterial activity; indole alkaloids; quinolone alkaloids.
Products