Dihydrophencomycin methyl ester, a new phenazine derivative from a marine Streptomycete

  • J Antibiot (Tokyo). 1997 Jun;50(6):479-83. doi: 10.7164/antibiotics.50.479.
K Pusecker  1 ,  H Laatsch ,  E Helmke ,  H Weyland
Affiliations
  • 1. Department of Organic Chemistry, University of Göttingen, Germany.
PMID: 9268003 DOI: 10.7164/antibiotics.50.479
Abstract

The novel 5,10-dihydrophencomycin methyl ester (4) and the known microbial metabolites (2-hydroxyphenyl)-acetamide (1), menaquinone MK9 (II, III, VIII, IX-H8) (2), and phencomycin (3a) were isolated from an unidentified marine Streptomyces sp. and the structures were elucidated by NMR methods. Compound 4 shows weak Antibiotic activity against Escherichia coli and Bacillus subtilis.

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