2. Cell Cycle/DNA Damage PI3K/Akt/mTOR Immunology/Inflammation
  3. ATM/ATR STING PD-1/PD-L1
  4. (Rac)-Lartesertib

(Rac)-Lartesertib  (Synonyms: (Rac)-M4076; (Rac)-ATM Inhibitor-5)

Cat. No.: HY-150617A
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(Rac)-Lartesertib ((Rac)-M4076) is an isoform of Lartesertib (HY-150617). Lartesertib (M4076) is an inhibitor of the serine/threonine protein kinase ATM with high potency. Lartesertib can inhibit the growth of multiple hematopoietic cell lines. Additionally, when combined with the ATR inhibitor Tuvusertib (HY-111451), Lartesertib can promote the death of tumor cells, activate the immune signaling pathway, and exhibit anti-tumor activity.

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(Rac)-Lartesertib

(Rac)-Lartesertib Estructura química

No. CAS : 2020089-41-0

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Other Forms of (Rac)-Lartesertib:

(Rac)-Lartesertib Related Antibodies

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Descripciòn

(Rac)-Lartesertib ((Rac)-M4076) is an isoform of Lartesertib (HY-150617). Lartesertib (M4076) is an inhibitor of the serine/threonine protein kinase ATM with high potency. Lartesertib can inhibit the growth of multiple hematopoietic cell lines. Additionally, when combined with the ATR inhibitor Tuvusertib (HY-111451), Lartesertib can promote the death of tumor cells, activate the immune signaling pathway, and exhibit anti-tumor activity[1][2].

Peso molecular

448.45

Fòrmula

C23H21FN6O3
No. CAS
SMILES

O=C1N(C2=C(N1C)C=NC3=C2C=C(C4=CN(C)N=C4C)C(OC)=C3)C5=C(OC)C=NC=C5F
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
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(Rac)-Lartesertib Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(Rac)-Lartesertib2020089-41-0(Rac)-M4076(Rac)-ATM Inhibitor-5ATM/ATRSTINGPD-1/PD-L1Ataxia telangiectasia mutatedATM and RAD3 relatedStimulator of Interferon GenesTMEM173MITAERISMPYSPD-1/Programmed death-ligand 1ataxia telangiectasia mutated kinaseATMprotein kinasePharmaceuticalInhibitorinhibitorinhibit

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(Rac)-Lartesertib
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HY-150617A
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