(S,R,S)-AHPC-amido-C7-acid
Based on 1 Customer Validation
(S,R,S)-AHPC-amido-C7-acid incorporates a VHL ligand for the E3 ubiquitin ligase and a PROTAC linker. (S,R,S)-AHPC-amido-C5-acid can be used to design PROTACs.
For research use only. We do not sell to patients.
- Purity: 98.71%
- CAS No.: 2172819-76-8
- Formula: C31H44N4O6S
- Molecular Weight:600.77
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Storage:
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
All E3 Ligase Ligand-Linker Conjugates Isoforms
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Biological Activity
Chemical Information
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CAS No. 2172819-76-8
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Appearance Solid
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Molecular Weight 600.77
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Formula C31H44N4O6S
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Color White to off-white
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SMILES
OC(CCCCCCCC(N[C@@H](C(C)(C)C)C(N1[C@@H](C[C@H](C1)O)C(NCC2=CC=C(C3=C(C)N=CS3)C=C2)=O)=O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
DMSO : ≥ 100 mg/mL (166.45 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (270 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.6645 mL | 8.3227 mL | 16.6453 mL | 41.6133 mL |
| 5 mM | 0.3329 mL | 1.6645 mL | 3.3291 mL | 8.3227 mL | |
| 10 mM | 0.1665 mL | 0.8323 mL | 1.6645 mL | 4.1613 mL | |
| 15 mM | 0.1110 mL | 0.5548 mL | 1.1097 mL | 2.7742 mL | |
| 20 mM | 0.0832 mL | 0.4161 mL | 0.8323 mL | 2.0807 mL | |
| 25 mM | 0.0666 mL | 0.3329 mL | 0.6658 mL | 1.6645 mL | |
| 30 mM | 0.0555 mL | 0.2774 mL | 0.5548 mL | 1.3871 mL | |
| 40 mM | 0.0416 mL | 0.2081 mL | 0.4161 mL | 1.0403 mL | |
| 50 mM | 0.0333 mL | 0.1665 mL | 0.3329 mL | 0.8323 mL | |
| 60 mM | 0.0277 mL | 0.1387 mL | 0.2774 mL | 0.6936 mL | |
| 80 mM | 0.0208 mL | 0.1040 mL | 0.2081 mL | 0.5202 mL | |
| 100 mM | 0.0166 mL | 0.0832 mL | 0.1665 mL | 0.4161 mL |