(S,R,S)-AHPC-O-PEG1-propargyl
Based on 1 Customer Validation
(S,R,S)-AHPC-O-PEG1-propargyl (Compound 10b) is an E3 ligand for the synthesis of PROTAC. (S,R,S)-AHPC-O-PEG1-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
For research use only. We do not sell to patients.
- Purity : 98.35%
- CAS No.: 2098799-79-0
- Formula: C29H38N4O6S
- Molecular Weight:570.70
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
All E3 Ligase Ligand-Linker Conjugates Isoforms
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Biological Activity
Description
Chemical Information
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CAS No. 2098799-79-0
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Appearance Solid
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Molecular Weight 570.70
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Formula C29H38N4O6S
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Color Light yellow to yellow
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SMILES
O=C(N(C[C@@H]1O)[C@@H](C1)C(NCC2=CC=C(C(SC=N3)=C3C)C=C2)=O)[C@H](C(C)(C)C)NC(COCCOCC#C)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
In Vitro:
DMSO : 50 mg/mL (87.61 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (272 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.7522 mL | 8.7612 mL | 17.5223 mL | 43.8059 mL |
| 5 mM | 0.3504 mL | 1.7522 mL | 3.5045 mL | 8.7612 mL | |
| 10 mM | 0.1752 mL | 0.8761 mL | 1.7522 mL | 4.3806 mL | |
| 15 mM | 0.1168 mL | 0.5841 mL | 1.1682 mL | 2.9204 mL | |
| 20 mM | 0.0876 mL | 0.4381 mL | 0.8761 mL | 2.1903 mL | |
| 25 mM | 0.0701 mL | 0.3504 mL | 0.7009 mL | 1.7522 mL | |
| 30 mM | 0.0584 mL | 0.2920 mL | 0.5841 mL | 1.4602 mL | |
| 40 mM | 0.0438 mL | 0.2190 mL | 0.4381 mL | 1.0951 mL | |
| 50 mM | 0.0350 mL | 0.1752 mL | 0.3504 mL | 0.8761 mL | |
| 60 mM | 0.0292 mL | 0.1460 mL | 0.2920 mL | 0.7301 mL | |
| 80 mM | 0.0219 mL | 0.1095 mL | 0.2190 mL | 0.5476 mL |