2098799-79-0
Chemical Structure
(S,R,S)-AHPC-O-PEG1-propargyl
- CAS No.: 2098799-79-0
- Formula:C29H38N4O6S
- Molecular Weight:570.70
IUPAC Name: (2S,4R)-1-((S)-3,3-dimethyl-2-(2-(2-(prop-2-yn-1-yloxy)ethoxy)acetamido)butanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide
InChIKey: GZSOURYSHDAJDX-MVERNJQCSA-N
SMILES: O=C(N(C[C@@H]1O)[C@@H](C1)C(NCC2=CC=C(C(SC=N3)=C3C)C=C2)=O)[C@H](C(C)(C)C)NC(COCCOCC#C)=O
Biological Activity: (S,R,S)-AHPC-O-PEG1-propargyl (Compound 10b) is an E3 ligand for the synthesis of PROTAC[1]. (S,R,S)-AHPC-O-PEG1-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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(S,R,S)-AHPC-O-PEG1-propargyl | (S,R,S)-AHPC-O-PEG1-propargyl (Compound 10b) is an E3 ligand for the synthesis of PROTAC. (S,R,S)-AHPC-O-PEG1-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | |||||||||||||||||||||
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Keywords