NSG2 - neuronal vesicle trafficking associated 2 Gene

Also Known as CALY3; HMP19

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 51617

About NSG2

Cytogenetic location: 5q35.2 Genomic coordinates (GRCh38): 5:174,045,706-174,109,179 (from NCBI)

This gene has 9 transcripts (splice variants), 190 orthologues and 2 paralogues. Biased expression in brain (RPKM 115.2) and adrenal (RPKM 19.2).

Summary

Predicted to enable Clathrin light chain binding activity. Predicted to be involved in Clathrin coat assembly and endosomal transport. Located in Golgi apparatus. [provided by Alliance of Genome Resources, Apr 2022]

NSG2 Products (1)

mRNA Protein Name
NM_015980.5 NP_057064.1 neuronal vesicle trafficking-associated protein 2

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
28514442 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

NSG2 Protein Structure

Calcyon

Calcyon: D1 dopamine receptor-interacting protein (calcyon) (1 - 169)

  • 0
  • 100
  • 171 a.a.
Protein Preferred Names Protein Names

neuronal vesicle trafficking-associated protein 2

  • calcyon family member 3

NSG2 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
NSG2 Q9Y328 HSPA5 Homo sapiens P11021
Anti Tag CoIP
33961781
Intra
NSG2 Q9Y328 HSPA5 Homo sapiens P11021
Anti Tag CoIP
28514442
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Nipah Virus Encephalitis

  • Equine Morbillivirus
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09594 NSG2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta NSG2 VGNC VGNC:75457
Felis catus NSG2 VGNC VGNC:63888
Bos taurus NSG2 VGNC VGNC:58607
Canis familiaris NSG2 VGNC VGNC:51908
Rattus norvegicus NSG2 RGD RGD:1563944
Mus musculus NSG2 MGD MGI:1202070
Others NSG2 NCBI