Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
313 Results for "
antisense
" in MedChemExpress (MCE) Product Catalog:
Products (313)
313 Results for "antisense" in MCE Product Catalog:
Cat. No.: HY-W800791
CAS No.: 115288-21-6
16:0 Caproylamine PE is an amide-functionalized lipid with a phosphoethanolamine linked to two palmitic acid tails.
Cat. No.: HY-W800792
CAS No.: 111613-33-3
Synonyms: 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-(succinyl)
18:1 Succinyl PE is a carboxylic acid-functionalized lipid with a two carbon linker to a phosphoethanolamine bound to two oleic acid tails.
Cat. No.: HY-W800793
CAS No.: 186800-61-3
Synonyms: 1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-(succinyl)
16:0 Succinyl PE is a carboxylic acid-functionalized lipid with a two carbon linker to a phosphoethanolamine bound to two palmitic acid tails.
Cat. No.: HY-W800794
CAS No.: 474923-45-0
Synonyms: DPPE-NG; 1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-(glutaryl)
16:0 Glutaryl PE is is a carboxylic acid-functionalized lipid with a three carbon linker to a phosphoethanolamine bound to two palmitic acid tails.
Cat. No.: HY-W800795
CAS No.: 474923-47-2
Synonyms: DOPE-NG; 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-(dodecanoyl)
18:1 Dodecanyl PE is a carboxylic acid-functionalized lipid with a ten carbon linker to a phosphoethanolamine bound to two oleic acid tails.
Cat. No.: HY-W800796
CAS No.: 384835-53-4
Synonyms: 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-(biotinyl)
18:1 Biotinyl PE is a biotin-functionalized lipid attached to a phosphoethanolamine linked to two oleic acid groups.
Cat. No.: HY-W800797
CAS No.: 384835-54-5
Synonyms: 1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-(biotinyl)
16:0 Biotinyl PE is a biotin-functionalized lipid attached to a phosphoethanolamine linked to two palmitic acid groups.
Cat. No.: HY-W800798
CAS No.: 1246304-37-9
Synonyms: 1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-(cyanur)
16:0 Cyanur PE is a cyanur-functionalized lipid attached to a phosphoethanolamine linked to two palmitic acid groups.
Cat. No.: HY-W800825
CAS No.: 123233-50-1
Octadecanedioic Acid Mono-L-carnitine ester is a cationic lipid which may be used in combination with other lipids in the formation of lipid nanoparticles (LNPs). Its terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. HATU) to form a stable amide bond.
Cat. No.: HY-W800843
CAS No.: 2627085-42-9
tert-Butyl 3-(7-((undecan-3-yloxy)carbonyl)heptylamino)propylcarbamate is an aminolipid featuring a Boc-protected primary amine, a propylamine spacer attached to an octanoate chain and a C11 chain.
Cat. No.: HY-188137
Research Areas:
ASO-5005 is a 20-mer Gapmer antisense oligonucleotide modified with locked nucleic acids (LNA), featuring a full phosphorothioate backbone, which targets BCL2 mRNA and BCL2L1 mRNA. ASO-5005 downregulates Bcl-2 expression via an RNase H-dependent mechanism, with its sequence fully complementary to BCL2 mRNA; it simultaneously downregulates Bcl-xL expression via an RNase H-dependent mechanism, with three mismatches between its sequence and BCL2L1 mRNA, while LNA modification enhances its activity against this mismatched target. ASO-5005 induces Apoptosis by activating Caspase-3 and cleaving ICAD. ASO-5005 does not significantly regulate the expression of Bcl-W, Survivin, Akt, or p53 in tumor cells. ASO-5005 can be used for research on breast cancer and non-small cell lung cancer .
Cat. No.: HY-W048513
CAS No.: 60129-59-1
Cat. No.: HY-156215
CAS No.: 802835-01-4
Target:
Research Areas:
NCI-B16 is a small molecule RNA binder obtained through RNA-small molecule interaction screening. NCI-B16 interacts with RNA motifs under competitive conditions. NCI-B16 is used for RNA-small molecule interaction studies .
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
