22 Results for "

ASCT

" in MedChemExpress (MCE) Product Catalog:
Products (22)

22 Results for "ASCT" in MCE Product Catalog:

  • Targets Recommended:
Cat. No.: HY-P81435A
Synonyms: SLC1A5 ; ASCT2; M7V1, RDR, RDRC; Neutral amino acid transporter B(0); ATB(0); Baboon M7 virus receptor; RD114/simian type D retrovirus receptor; Sodium-dependent neutral amino acid transporter type 2; Solute carrier family 1 member 5

Host:  

Rabbit

Application:  

IHC-P

Reactivity:  

Human

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Cat. No.: HY-19867
CAS No.: 1191448-17-5
Synonyms: TG-0054
Target:  

CXCR

Research Areas:  

Cancer

Burixafor (TG-0054) is a potent CXCR4 antagonist with a pIC50 of 7.4. Burixafor inhibits the binding of CXCL12 to CXCR4, antagonizes CXCL12-induced recruitment of Gαᵢ and β-arrestin2, and blocks the downstream Gαᵢ-mediated inhibitory effect on cAMP signal transduction. Burixafor mobilizes CD34 + hematopoietic stem/progenitor cells (HSPC) from the bone marrow to the peripheral blood. Burixafor can be used for research on autologous hematopoietic stem cell transplantation (ASCT) .
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