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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
37 Results for "
Selenium
" in MedChemExpress (MCE) Product Catalog:
Products (37)
37 Results for "Selenium" in MCE Product Catalog:
Cat. No.: HY-W585825
CAS No.: 2578-27-0
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Selenoethionine is a selenium-containing amino acid .
Cat. No.: HY-151188
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DHU-Se1 is a potent anti-inflammatory agent. DHU-Se1 can stimulate macrophages to release the reactive selenium compound and reduce the expression of cellular inflammatory factors (eg: iNOS and TNF-α). DHU-Se1 alleviate the process of inflammation by blocking the polarization of macrophages from M0 to M1 .
Cat. No.: HY-W540926
CAS No.: 75006-64-3
Synonyms: Biacetyl dioxime sodium hydrate
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Dimethylglyoxime sodium hydrate (Biacetyl dioxime sodium hydrate) is an oxime compound. Dimethylglyoxime sodium hydrate selectively coordinates with divalent nickel ions Ni 2+ to form stable complexes, and can also coordinate with copper ions Cu 2+, but does not coordinate with iron, selenium or zinc. Dimethylglyoxime sodium hydrate inhibits the aggregation of human β-amyloid 40 peptide in vitro. Dimethylglyoxime sodium hydrate is used in the research of Alzheimer's disease .
Cat. No.: HY-114851
CAS No.: 26046-89-9
Synonyms: GMSeC
Methylselenocarboxyethylglutamine (GMSeC) is an organic selenium compound that shows no in vitro anti-cancer activity against colon cancer .
Cat. No.: HY-112549
CAS No.: 106154-18-1
Synonyms: 5-KETE
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5-oxo-ETE is a potent chemoattractant for eosinophils. 5-oxo-ETE inhibits selenium-induced apoptosis in prostate cancer cells. 5-oxo-ETE can be used in research into asthma, allergic diseases, cancer and cardiovascular disease .
Cat. No.: HY-159004
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Se-DOPE is a phospholipid molecule with selenium. Se-DOPE can be used to synthesize the bifunctional Janus liposozyme. Se-DOPE promotes the production of ROS with induction of lights, scavenges the ROS with the presence of glutathione. Se-DOPE regulates redox and immune homeostasis in infected diabetic wounds .
Cat. No.: HY-146464
CAS No.: 2422019-91-6
Antifungal agent 30 (compound A18) is a potent antifungal agent. Antifungal agent 30 shows excellent antifungal activity against Candida albicans (CPCC400616) and Aspergillus fumigatus, with MIC of 0.03 and 0.5 μg/mL, respectively. Antifungal agent 30 also shows excellent antifungal activity against fluconazole-resistant strains. The potent antifungal activity of Antifungal agent 30 mainly causes by hydrogen and coordination bond interaction with the CYP51 .
Cat. No.: HY-184610
Selenium is an essential trace element for the human body, playing a vital role in various physiological activities and significantly impacting human health. Selenium deficiency can lead to a variety of diseases, while excessive amounts may be toxic. In recent years, selenium nanoparticles (SeNPs) have attracted increasing attention due to their excellent biocompatibility, low toxicity, and high antioxidant activity, making them suitable for a wide range of applications. Particularly in the fields of biomedicine, nutritional supplementation, food preservation, and environmental remediation, selenium nanoparticles hold immense application potential.
Cat. No.: HY-159915
Se2h is a cruzain inhibitor that exhibits strong activity against the intracellular amastigotes of Trypanosoma cruzi (EC50 < 1 μM, SI > 10), with an inhibitory activity against cruzain of IC50 < 100 nM (SI > 5.55). Compared to Benznidazole (HY-B1548) and the cruzain inhibitor K777 (HY-119293), Se2h shows superior selectivity and inhibition, while its selenazole structure reduces selenium-related toxicity. Se2h exhibits antiparasitic activity and holds promise for research in Chagas disease .
Cat. No.: HY-184611
Selenium (Se) is an essential trace element for the human body, playing a vital role in various physiological activities. In the body, selenium is bound to selenocysteine, an amino acid used to synthesize several selenoproteins. Selenium is often the active site of these proteins, playing a crucial role in maintaining intracellular redox balance. Chitosan-stabilized selenium nanoparticles (CS-SeNPs) are nanomaterials using the biopolymer chitosan (CS) as a stabilizer. Through electrostatic interactions, chitosan coats the surface of selenium nanoparticles (Se NPs), improving their dispersibility, stability, and biocompatibility. Se NPs themselves are characterized by low toxicity and high bioactivity, and the introduction of chitosan further enhances their functionality and application potential, making them widely recognized in biomedicine, food, and agriculture.
Cat. No.: HY-B1000S
CAS No.: 2108158-10-5
Synonyms: Seleno-DL-methionine-76Se; DL-Selenomethionine-76Se
Cat. No.: HY-158616
CAS No.: 1286479-53-5
Cat. No.: HY-184989
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PD-L1-IN-12 is an orally active and potent selenium-containing small-molecule PD-L1 inhibitor (KD = 9.06 nM). PD-L1-IN-12 can mediate the internalization of PD-L1 and strongly block hPD-1 and hPD-L1 interaction (IC50 = 5.2 nM). PD-L1-IN-12 can be used in colorectal cancer immunology research .
Cat. No.: HY-K3036
MCE IMDM (Iscove's Modified Dulbecco's Medium) is an enriched formulation modified from DMEM, containing high concentrations of glucose, sodium pyruvate, amino acids, vitamins, HEPES buffer, selenium, and other essential nutrients. It is designed to meet the nutritional requirements for rapid cell proliferation and high-density culture, supporting a variety of cell types, including Jurkat cells, COS-7 cells, and macrophages. The product specifications are based on the 500 mL format, and larger volume packages are provided as multiples of this standard specification.
Cat. No.: HY-101966R
CAS No.: 1916571-90-8
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NCT-503 (Standard) is the analytical standard of NCT-503 (HY-101966). This product is intended for research and analytical applications. NCT-503 is a blood-brain barrier-permeable, non-competitive PHGDH inhibitor with an IC50 of 2.5 μM against human PHGDH. NCT-503 reduces glucose-derived serine production and the incorporation of one-carbon units into nucleotides without decreasing PHGDH protein expression. NCT-503 prevents high selenium-induced insulin resistance in mice by regulating blood glucose and insulin levels and improving glucose tolerance, and also inhibits the growth of tumors overexpressing PHGDH. NCT-503 can be used in research related to insulin resistance and breast cancer .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
