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SELENBP1 (Selenium Binding Protein 1) Antibody (YA7832)(PBS only)

(Synonyms: HEL-S-134P; hSBP; LPSB; SBP56; SP56)

SELENBP1 (Selenium Binding Protein 1) Antibody (YA7832) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to SELENBP1 (Selenium Binding Protein 1).

For research use only. We do not sell to patients.
  • Host:

    Mouse

  • Isotype:

    IgG2a

  • Application:

    WB, IHC-P

  • Reactivity :

    Human, Mouse, Rat

  • Formulation:

    Supplied in PBS, pH 7.4.

  • Conjugation:
    Non-conjugated
  • SELENBP1 (Selenium Binding Protein 1) Antibody (YA7832)(PBS only) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Applications

Application
WB Info
WB: Western Blot
IHC-P Info
IHC-P: Immunohistochemistry-Paraffin
Dilution Ratio 1:500-2000 1:150-500

Product Details

Description

SELENBP1 (Selenium Binding Protein 1) Antibody (YA7832) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to SELENBP1 (Selenium Binding Protein 1).

  • Host Mouse
  • Species Reactivity
    Human, Mouse, Rat
  • Calculated Molecular Weight Predicted band size: 52.2 kDa
Immunogen

Full length human recombinant protein of human SELENB1 produced in HEK293T cell.

Purification

Affinity purified

Conjugation

Non-conjugated

Isotype

IgG2a

Product Properties

  • Appearance

    Liquid

  • Formulation

    Supplied in PBS, pH 7.4.

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    SELENBP1 catalyzes the oxidation of methanethiol, an organosulfur compound known to be produced in substantial amounts by gut bacteria. Selenium-binding protein which may be involved in the sensing of reactive xenobiotics in the cytoplasm. May be involved in intra-Golgi protein transport[1].

  • Subcellular Localization

    Nucleus,Cytoplasm, cytosol,Membrane

  • Expression


    Tissue_Specificity: Widely expressed. Highly expressed in liver, lung, colon, prostate, kidney and pancreas. In brain, present both in neurons and glia (at protein level). Down-regulated in lung adenocarcinoma, colorectal carcinoma and ovarian cancer. Two-fold up-regulated in brain and blood from schizophrenia patients
    Induction: Down-regulated by androgen in prostate cancer cells

  • Isoforms & Post-Translational Modification

    Q13228 has four isomers: Q13228-1: 52391 Da (predicted); Q13228-2: 45349 Da (predicted); Q13228-3: 45469 Da (predicted); Q13228-4: 56866 Da (predicted).
    Phosphorylated丨The N-terminus is blocked

  • Subunit

    Interacts with USP33

  • SwissProt ID

    Q13228

  • Synonyms

    HEL-S-134P; hSBP; LPSB; SBP56; SP56

SELENBP1 (Selenium Binding Protein 1) Antibody (YA7832)(PBS only) Related Classifications

MOQ
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100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
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  • SELENBP1 (Selenium Binding Protein 1) Antibody (YA7832)(PBS only) Product Image