41 Results for "

Ganglionic blocker

" in MedChemExpress (MCE) Product Catalog:
Products (41)

41 Results for "Ganglionic blocker" in MCE Product Catalog:

Cat. No.: HY-187689
CAS No.: 1005056-10-9
Target:  

Arrestin

Research Areas:  

Cancer

RKN5755 is a β-arrestin1 inhibitor and a selective inhibitor of activated fibroblasts. RKN5755 binds to β-arrestin1 and interferes with the cofilin signaling pathway mediated by this protein to block its function. RKN5755 not only inhibits the enhanced migratory effect of fibroblasts co-cultured with cancer cells, but also prevents the inhibitory effect of EP3 agonists on the EP2 receptor-induced elevation of tetrodotoxin-resistant sodium currents in mouse dorsal root ganglion neurons. RKN5755 is widely used in research on related diseases such as cancer metastasis and pain .
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