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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
130 Results for "
(M-R,V-R)S. aureus
" in MedChemExpress (MCE) Product Catalog:
Products (130)
130 Results for "(M-R,V-R)S. aureus" in MCE Product Catalog:
Cat. No.: HY-E70899A
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Topoisomerase IV, Staphylococcus aureus (EC 5.99.1.) is prepared by overexpressing the subunits in E.coli.
Cat. No.: HY-E70940
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Sphingomyelinase, Staphylococcus aureus (EC 3.1.4.12) is a hydrolase enzyme that is involved in sphingolipid metabolism reactions. Sphingomyelinase is a member of the DNase I superfamily of enzymes and is responsible for breaking sphingomyelin (SM) down into phosphocholine and ceramide.
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(+)-trans-Limonene oxide is an antimicrobial essential oil component with activity against Staphylococcus aureus. (+)-trans-Limonene oxide acts as a selective agent for drug-resistant bacterial mutants without increasing the mutation frequency of Staphylococcus aureus USA300. (+)-trans-Limonene oxide can be used in studies of Staphylococcus aureus infection .
Cat. No.: HY-N15435A
Conimine TFA is a steroidal alkaloid, antibacterial agent and potentiator. Conimine TFA is isolated from the seeds of Holarrhena antidysenteriaca Wall.ex A.DC. Conimine TFA exhibits intrinsic antibacterial activity against methicillin-sensitive Staphylococcus aureus and methicillin-resistant Staphylococcus aureus. When combined with Penicillin, Conimine TFA shows synergistic antibacterial effects against methicillin-resistant Staphylococcus aureus; when combined with Vancomycin (HY-B0671), it exerts synergistic antibacterial effects against both methicillin-sensitive and methicillin-resistant Staphylococcus aureus .
Cat. No.: HY-186107
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ZY36 is a SaClpP agonist with an EC50 of 1.01 μM against Staphylococcus aureus. ZY36 activates SaClpP-mediated proteolysis. ZY36 inhibits the growth of Staphylococcus aureus. ZY36 is applicable to studies related to Staphylococcus aureus infections, such as peritonitis .
Cat. No.: HY-N19935
CAS No.: 30390-05-7
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Cat. No.: HY-181835
CAS No.: 1448066-54-3
AgrC-IN-1 is an AgrC inhibitor with an IC50 of 3.5 μM against Staphylococcus aureus AgrC. AgrC-IN-1 competitively binds to AgrC, inhibiting its autophosphorylation activity in Staphylococcus aureus. AgrC-IN-1 inhibits quorum sensing in Staphylococcus aureus, blocking virulence factor production. AgrC-IN-1 can be used for the research of Staphylococcus aureus infections .
Cat. No.: HY-W041958
CAS No.: 16078-71-0
5-Amino-4-carbethoxy-1-phenylpyrazole is a pyrazole derivative that inhibits biofilm formation by Staphylococcus aureus strains without exerting significant inhibitory effects on the growth of planktonic bacteria. 5-Amino-4-carbethoxy-1-phenylpyrazole can be used in studies related to Staphylococcus aureus infections .
Cat. No.: HY-185443
CAS No.: 1922152-04-2
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UCP1172 is an antibacterial (Antibacterial) agent and Dihydrofolate reductase inhibitor, with an IC50 of 0.0089 μM against Staphylococcus aureus DfrB, 0.22 μM against DfrG, 0.41 μM against DfrA, and 0.030 μM against DfrK. UCP1172 potently inhibits the growth of MRSA/MSSA isolates carrying dfrG and dfrK (MIC values of 0.3125-0.625 μg/mL), shows weak activity against MRSA carrying dfrA (MIC of 5 μg/mL), and exerts extremely potent inhibitory effects on wild-type S. aureus ATCC 43300 (MIC of 0.0098 μg/mL). UCP1172 can be used in studies related to tuberculosis and Staphylococcus aureus infections .
Cat. No.: HY-186108
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ZY38 is a SaClpP agonist that activates SaClpP-mediated α-casein hydrolysis with an EC50 of 1.52 μM. ZY38 exhibits bactericidal activity against Staphylococcus aureus. ZY38 is applicable to studies related to Staphylococcus aureus infections, such as peritonitis .
Cat. No.: HY-W034984
CAS No.: 12266-92-1
(1,5-Cyclooctadiene) dimethylplatinum (II) (Compound Pt3) is an Antibacterial agent. (1,5-Cyclooctadiene) dimethylplatinum (II) exhibits limited but selective activity against some Gram-positive Staphylococcus aureus strains, including methicillin-resistant Staphylococcus aureus (MRSA) and Glycopeptide-intermediate Staphylococcus aureus (GISA). (1,5-Cyclooctadiene) dimethylplatinum (II) shows no hemolytic activity .
Cat. No.: HY-N19151
CAS No.: 2241205-03-6
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Antibacterial agent 363 is a penicillin derivative and antibacterial agent with inhibitory activity against Staphylococcus aureus. Antibacterial agent 363 can be used in studies related to drug-resistant Staphylococcus aureus infections .
Cat. No.: HY-181177
Antibacterial agent 320, 1,5-disubstituted 1,2,3-triazole derivative, is an antibacterial agent. Antibacterial agent 320 exerts strong antibacterial activity against Pseudomonas aeruginosa and Staphylococcus aureus. Antibacterial agent 320 can be used for the research of bacterial infection .
Cat. No.: HY-186109
CAS No.: 2999673-51-5
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ZY39 is a SaClpP agonist. ZY39 promotes the enzymatic hydrolysis of SaClpP and HsClpP in vitro. ZY39 inhibits the growth of Staphylococcus aureus strains. ZY39 reduces the load of Staphylococcus aureus in organs and ascites in mouse peritonitis models and zebrafish infection models, and improves the survival rate of model animals. ZY39 can be used in studies related to Staphylococcus aureus infection, such as peritonitis .
Cat. No.: HY-182033
CAS No.: 2761081-10-9
ClpP agonist 1 is a Staphylococcus aureus ClpP (SaClpP) agonist with an EC50 of 1.44 μM, Kd values of 2.95 μM (isothermal titration calorimetry) and 18 μM (bio-layer interferometry), and a low drug resistance frequency. ClpP agonist 1 reduces bacterial load, shrinks infected area and improves histopathological outcomes in a mouse skin infection model. ClpP agonist 1 can be used for the research of Methicillin (HY-121544)-resistant Staphylococcus aureus (MRSA) skin infections .
Cat. No.: HY-129473
CAS No.: 82422-62-6
JCP678 is a selective inhibitor of Staphylococcus aureus serine hydrolase (FphF). JCP678 blocks the labeling of FphF by serine-reactive activity probes. JCP678 is applicable to research related to Staphylococcus aureus infections .
Cat. No.: HY-178213
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Antibacterial agent 295 is nitrofuran derivative. Antibacterial agent 295 is an antibiotic with anti-bacterial effects to S. aureus and E.coli. Antibacterial agent 295 showes an MIC of 0.78 μM in S. aureus USA300 and 1.6 μM in E.coli K12. Antibacterial agent 295 can be used for the research of infection .
Cat. No.: HY-N20670
CAS No.: 1192767-71-7
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
