1448066-54-3
1448066-54-3
Chemical Structure
AgrC-IN-1
- CAS No.: 1448066-54-3
- Formula:C18H15ClN4O2S2
- Molecular Weight:418.92
InChIKey: CCUQPZZDLZKQON-UHFFFAOYSA-N
SMILES: ClC1=CC(NC(N2CCC(N=C(NC(C3=CSC=C3)=O)S4)=C4C2)=O)=CC=C1
Biological Activity: AgrC-IN-1 is an AgrC inhibitor with an IC50 of 3.5 μM against Staphylococcus aureus AgrC. AgrC-IN-1 competitively binds to AgrC, inhibiting its autophosphorylation activity in Staphylococcus aureus. AgrC-IN-1 inhibits quorum sensing in Staphylococcus aureus, blocking virulence factor production. AgrC-IN-1 can be used for the research of Staphylococcus aureus infections[1].
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AgrC-IN-1 | AgrC-IN-1 is an AgrC inhibitor with an IC50 of 3.5 μM against Staphylococcus aureus AgrC. AgrC-IN-1 competitively binds to AgrC, inhibiting its autophosphorylation activity in Staphylococcus aureus. AgrC-IN-1 inhibits quorum sensing in Staphylococcus aureus, blocking virulence factor production. AgrC-IN-1 can be used for the research of Staphylococcus aureus infections. | |||||||||||||||||||||
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References
Keywords
