468-41-7
Chemical Structure
Conimine
- CAS No.: 468-41-7
- Formula:C22H36N2
- Molecular Weight:328.53
InChIKey: SHCHXCXYUPHKHW-QLPKIABKSA-N
SMILES: C[C@H]1[C@]2([H])[C@]3(CN1)[C@](CC2)([H])[C@@]4([H])[C@]([C@@]5(C(C[C@H](CC5)NC)=CC4)C)([H])CC3
Biological Activity: Conimine is a steroidal alkaloid, antibacterial agent and potentiator. Conimine is isolated from the seeds of Holarrhena antidysenteriaca Wall.ex A.DC. Conimine exhibits intrinsic antibacterial activity against methicillin-sensitive Staphylococcus aureus and methicillin-resistant Staphylococcus aureus. When combined with Penicillin, Conimine shows synergistic antibacterial effects against methicillin-resistant Staphylococcus aureus; when combined with Vancomycin (HY-B0671), it exerts synergistic antibacterial effects against both methicillin-sensitive and methicillin-resistant Staphylococcus aureus[1].
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Conimine | Conimine is a steroidal alkaloid, antibacterial agent and potentiator. Conimine is isolated from the seeds of Holarrhena antidysenteriaca Wall.ex A.DC. Conimine exhibits intrinsic antibacterial activity against methicillin-sensitive Staphylococcus aureus and methicillin-resistant Staphylococcus aureus. When combined with Penicillin, Conimine shows synergistic antibacterial effects against methicillin-resistant Staphylococcus aureus; when combined with Vancomycin (HY-B0671), it exerts synergistic antibacterial effects against both methicillin-sensitive and methicillin-resistant Staphylococcus aureus. | |||||||||||||||||||||
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