5-Amino-4-carbethoxy-1-phenylpyrazole
Based on 1 Customer Validation
5-Amino-4-carbethoxy-1-phenylpyrazole is a pyrazole derivative that inhibits biofilm formation by Staphylococcus aureus strains without exerting significant inhibitory effects on the growth of planktonic bacteria. 5-Amino-4-carbethoxy-1-phenylpyrazole can be used in studies related to Staphylococcus aureus infections.
For research use only. We do not sell to patients.
- CAS No.: 16078-71-0
- Formula: C12H13N3O2
- Molecular Weight:231.25
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
In Vitro
5-Amino-4-carbethoxy-1-phenylpyrazole (Compound 2) (0.3-300 μM; 24 h) inhibits biofilm formation in Staphylococcus aureus ATCC 6538, ATCC 25923, and ATCC 29213 with IC50 values of 95 μM, 222 μM, and 34 μM, respectively, without affecting planktonic bacterial growth[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Chemical Information
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CAS No. 16078-71-0
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Appearance Solid
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Molecular Weight 231.25
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Formula C12H13N3O2
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SMILES
CCOC(=O)C1=C(N)N(N=C1)C1=CC=CC=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Protocols
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Fungal Biofilm Culture
Fungal biofilm culture is an in vitro method for growing surface-attached fungal communities, most commonly Candida albicans, on abiotic substrates such as polystyrene wells, silicone elastomer, or polymethylmethacrylate; the assay models adhesion, proliferation, filamentation, extracellular-matrix-associated maturation, and dispersion. Biofilm output can be read by optical density at 600 nm for adherent biomass, XTT reduction for metabolic activity, CFU recovery for viable attached or dispersed cells, and microscopy for architecture.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
5-Amino-4-carbethoxy-1-phenylpyrazole Related Classifications
HY-W041958 Related Classifications
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