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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
193 Results for "
CSFs
" in MedChemExpress (MCE) Product Catalog:
Products (193)
193 Results for "CSFs" in MCE Product Catalog:
Cat. No.: HY-174732
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Human CSF3 mRNA encodes the human colony stimulating factor 3 (CSF3) protein, a member of the IL-6 superfamily of cytokines. CSF3 controls the production, differentiation, and function of granulocytes.
Cat. No.: HY-P991313
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Cat. No.: HY-153277
CAS No.: 2394874-63-4
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Axl/Mer/CSF1R-IN-2 (Comp 4) is a Axl, Mer and CSF1R inhibitor .
Cat. No.: HY-P990849
Cat. No.: HY-P990963
CAS No.: 2817686-50-1
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Cat. No.: HY-112446
CAS No.: 107761-24-0
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ST638 is a potent tyrosine kinase inhibitor (IC50=370 nM). ST638 also targets the CSF-1 receptor and inhibits PGE2 production .
Cat. No.: HY-174733
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Human CSF2RA mRNA encodes the human colony stimulating factor 2 receptor subunit alpha (CSF2RA) protein, a cytokine that controls the production, differentiation, and function of macrophages.
Cat. No.: HY-RS03227
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CSF1 Human Pre-designed siRNA Set A contains three designed siRNAs for CSF1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS03231
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CSF2 Human Pre-designed siRNA Set A contains three designed siRNAs for CSF2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS03234
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CSF3 Human Pre-designed siRNA Set A contains three designed siRNAs for CSF3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS23226
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Csf2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Csf2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS23394
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Csf3 Rat Pre-designed siRNA Set A contains three designed siRNAs for Csf3 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS03228
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CSF1R Human Pre-designed siRNA Set A contains three designed siRNAs for CSF1R gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS03229
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Csf1r Mouse Pre-designed siRNA Set A contains three designed siRNAs for Csf1r gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS03230
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Csf1r Rat Pre-designed siRNA Set A contains three designed siRNAs for Csf1r gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS03232
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CSF2RA Human Pre-designed siRNA Set A contains three designed siRNAs for CSF2RA gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS03233
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CSF2RB Human Pre-designed siRNA Set A contains three designed siRNAs for CSF2RB gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS03235
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CSF3R Human Pre-designed siRNA Set A contains three designed siRNAs for CSF3R gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-101774R
CAS No.: 2095849-04-8
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CSF1R-IN-1 (Standard) is the analytical standard of CSF1R-IN-1 (HY-101774). This product is intended for research and analytical applications. CSF1R-IN-1 is a CSF1R inhibitor with an with an IC50 of 0.5 nM.
Cat. No.: HY-187340
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CSF1R/c-Kit-IN-1 is a CSF-1R and c-Kit inhibitor, with an IC50 of 5.88 nM against human CSF-1R and an IC50 of 1.47 nM against human c-Kit. CSF1R/c-Kit-IN-1 binds to the ATP-binding pocket of CSF-1R, forming a hinge interaction with Cys666 via the oxazole nitrogen atom and adjacent amino group, and binds to residues in the hydrophobic binding pocket. CSF1R/c-Kit-IN-1 binds to the ATP-binding pocket of c-Kit, maintains a hinge interaction through its 2-amino-oxazole core, and binds to a broader hydrophobic surface near the solvent-exposed region via its morpholine substituent. CSF1R/c-Kit-IN-1 inhibits CSF-1-induced phosphorylation of ERK, which is a downstream readout of the CSF-1R signaling pathway. CSF1R/c-Kit-IN-1 can be used in the research of neuroinflammation-related neurodegenerative diseases .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
