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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
456 Results for "
O2
" in MedChemExpress (MCE) Product Catalog:
Products (456)
456 Results for "O2" in MCE Product Catalog:
Cat. No.: HY-E72042
Target:
Domaines de recherche:
Abieta-7,13-dien-18-ol hydroxylase (EC 1.14.13.109) is an oxidoreductase that can convert abieta-7,13-dien-18-ol, 2 reduced [NADPH--hemoprotein reductase] and 2 O2 into abieta-7,13-dien-18-oate, 2 oxidized [NADPH--hemoprotein reductase], 3 H2O and 3 H +.
Cat. No.: HY-E72038
Target:
Domaines de recherche:
9β-Pimara-7,15-diene oxidase (EC 1.14.13.144) is an oxidoreductase that can convert 9beta-pimara-7,15-diene, 3 reduced [NADPH--hemoprotein reductase] and 3 O2 into 9beta-pimara-7,15-dien-19-oate, 3 oxidized [NADPH--hemoprotein reductase], 4 H2O and 4 H +.
Cat. No.: HY-170938
Domaines de recherche:
AChE-IN-82 (compound 49) is an acetylcholinesterase (AChE) inhibitor. AChE-IN-82 inhibits eeAChE, eqBChE, hMAO-A, hMAO-B, and BACE-1 with IC50s of 0.072, 9.81, 14.52, 0.024, 2.42 μM, respectively. AChE-IN-82 inhibits COX-1, COX-2 and 5-LOX with IC50s of 60.41, 0.187, 0.18 μM, respectively. AChE-IN-82 shows an excellent neuroprotective effect by significantly reducing oxidative stress induced by H2 O2 .
Cat. No.: HY-N18465
CAS No.: 681152-39-6
Synonyms: 2''-O-(2'''-methylbutyryl)isoswertisin
Target:
Cat. No.: HY-W051271
CAS No.: 13463-67-7
Synonyms: Titanium dioxide
Domaines de recherche:
Titanium(IV) oxide is a photosensitizer and photocatalyst. Titanium(IV) oxide can be used as a pharmaceutical excipient such as a flow aid, coating agent, sunscreen, colorant, etc. Pharmaceutical excipients or pharmaceutical excipients refer to other chemical substances used in the pharmaceutical process other than the drug ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations that can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism and elimination (ADME) process of co-administered drugs. Titanium(IV) oxide can use light energy to generate electron-hole pairs to degrade pollutants. Photons excite electrons in TiO2 to generate active oxygen species (such as ·OH and ·O2 -), thereby oxidizing and mineralizing pollutants such as organic compounds and heavy metals. TiO2 can be used in the research of environmental remediation fields such as water treatment, air purification and self-cleaning materials [2] .
Cat. No.: HY-151650
CAS No.: 1254054-60-8
Target:
Domaines de recherche:
N3-O2Oc-O2Oc-OH is a click chemistry reagent containing an azide . N3-O2Oc-O2Oc-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Cat. No.: HY-D1065
CAS No.: 1392488-04-8
Cat. No.: HY-185272
CAS No.: 959755-19-2
Target:
Domaines de recherche:
3'-O-(2-Nitrobenzyl)-dCTP is a reversible terminator. 3'-O-(2-Nitrobenzyl)-dCTP can be recognized and incorporated by polymerases, thereby temporarily terminating primer extension during DNA synthesis. After incorporation into the extending DNA strand, 3'-O-(2-Nitrobenzyl)-dCTP temporarily halts the DNA polymerase extension reaction, and its 3'-O-(2-nitrobenzyl) blocking group can be removed by laser irradiation to regenerate a free 3'-OH for subsequent primer extension cycles. 3'-O-(2-Nitrobenzyl)-dCTP is applicable for resolving homopolymeric regions in DNA templates .
Cat. No.: HY-185274
CAS No.: 219607-49-5
Target:
Domaines de recherche:
3'-O-(2-Nitrobenzyl)-dTTP acts as a reversible terminator for DNA chain elongation. 3'-O-(2-Nitrobenzyl)-dTTP interacts with 9°N polymerase (exo-) A485L/Y409V, gets recognized and incorporated into the elongating DNA chain, thereby temporarily terminating the polymerase reaction. 3'-O-(2-Nitrobenzyl)-dTTP carries a 3'-O-(2-nitrobenzyl) blocking group, which can be removed by laser irradiation to regenerate the free 3'-OH − group and restore polymerase activity. 3'-O-(2-Nitrobenzyl)-dTTP is applicable in DNA sequencing studies .
Cat. No.: HY-W048491
CAS No.: 168427-74-5
Target:
Domaines de recherche:
2′-O-(2-Methoxyethyl)adenosine is an ATP (HY-B2176) derivative. 2′-O-(2-Methoxyethyl)adenosine can be used for oligonucleotide synthesis .
Cat. No.: HY-W048495
CAS No.: 223777-15-9
Target:
Domaines de recherche:
2'-O-(2-Methoxyethyl)-uridine is a synthetic oligonucleotide conversed from uridine. 2'-O-(2-Methoxyethyl)-uridine has the potential for chemotherapeutic agents development .
Cat. No.: HY-204504
CAS No.: 159351-98-1
Target:
Domaines de recherche:
42-O-(2-Aminoethyl)-rapamycin (compound 2.3) is a derivative of the mTOR inhibitor rapamycin. 42-O-(2-Aminoethyl)-rapamycin can be used in pharmaceutical research for developing conjugates .
Cat. No.: HY-177901
CAS No.: 159954-97-9
Target:
Domaines de recherche:
3'-O-(2-Nitrobenzyl)-dATP is a reversible and photolabile DNA synthesis terminator. 3'-O-(2-Nitrobenzyl)-dATP incorporates into growing DNA strands to terminate synthesis in a base-specific manner. 3'-O-(2-Nitrobenzyl)-dATP undergoes efficient photolytic removal of its 3'-protecting group upon UV exposure to enable reinitiation of DNA synthesis. 3'-O-(2-Nitrobenzyl)-dATP supports development of the Base Addition Sequencing Scheme (BASS) via a complete stop-start DNA synthesis cycle .
Cat. No.: HY-W048496
CAS No.: 223777-16-0
Target:
Domaines de recherche:
2'-O-(2-Methoxyethyl)-cytidine is a synthetic oligonucleotide derived from uridine. 2'-O-(2-Methoxyethyl)-cytidine has good hybridization properties and high stability, and can be used in the research of oligonucleotide chemotherapeutic agents .
Cat. No.: HY-185273
CAS No.: 959755-49-8
Target:
Domaines de recherche:
3'-O-(2-Nitrobenzyl)-dGTP is a reversible terminator. 3'-O-(2-Nitrobenzyl)-dGTP can be recognized and incorporated by DNA polymerases, thereby temporarily terminating DNA primer extension; after the 2-nitrobenzyl blocking group is removed via laser irradiation, a free 3'-OH can be regenerated to allow subsequent polymerase-mediated extension. 3'-O-(2-Nitrobenzyl)-dGTP can be used in DNA sequencing studies .
Cat. No.: HY-N7092S21
Synonyms: D(-)-Fructose-18O-2
Cat. No.: HY-B0389S31
Synonyms: Glucose-18O-2; D-(+)-Glucose-18O-2; Dextrose-18O-2
Cat. No.: HY-174866
CAS No.: 3055107-34-8
Domaines de recherche:
BT-O2C is a highly selective p300 PROTAC degrader. BT-O2C can significantly degrade the level of p300 in HAP1 cells. BT-O2C has significant cytotoxicity in CIC:DUX4 sarcoma (CDS) cell lines (IC50 ranges from 152 to 221 nM) and significantly reduces the expression of CDS target genes (ETV1, ETV4, ETV5). BT-O2C can be used for research on cancer .
Cat. No.: HY-137683A
Synonyms: GDPβS trisodium
Target:
Domaines de recherche:
Guanosine 5'-O-(2-thiodiphosphate) trisodium (GDPβS trisodium) is a non-hydrolyzable derivative of GDP. Guanosine 5'-O-(2-thiodiphosphate) trisodium acts as an inhibitor of adenylyl cyclase (AC) with a Ki value of 600 nM. In the absence of glutamic-pyruvic transaminase (GPT) in cerebral cortex membranes of rodent models, Guanosine 5'-O-(2-thiodiphosphate) trisodium partially activates AC with an EC50 of 400 nM. Guanosine 5'-O-(2-thiodiphosphate) trisodium prevents norepinephrine-induced nitric oxide release in ventricular myocytes [2] .
Cat. No.: HY-180123
CAS No.: 159351-89-0
Target:
Domaines de recherche:
42-O-(2-Azidoethyl)-Rapamycin (Compound 4) is an azide compound that can be used as a drug intermediate to synthesize the derivative of Rapamycin (HY-10219) .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
