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Cat. No.: HY-204504

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42-O-(2-Aminoethyl)-rapamycin

42-O-(2-Aminoethyl)-rapamycin (compound 2.3) is a derivative of the mTOR inhibitor rapamycin. 42-O-(2-Aminoethyl)-rapamycin can be used in pharmaceutical research for developing conjugates.

For research use only. We do not sell to patients.

CAS No.: 159351-98-1
Formula: C₅₃H₈₄N₂O₁₃
Molecular Weight:957.24

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

42-O-(2-Aminoethyl)-rapamycin Chemical Structure

CAS No.: 159351-98-1

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

42-O-(2-Aminoethyl)-rapamycin (compound 2.3) is a derivative of the mTOR inhibitor rapamycin. 42-O-(2-Aminoethyl)-rapamycin can be used in pharmaceutical research for developing conjugates^[1].

Chemical Information

CAS No. 159351-98-1
Molecular Weight 957.24
Formula C₅₃H₈₄N₂O₁₃
SMILES

CO[C@@H]1C[C@@H](CC[C@H]1OCCN)C[C@H]([C@@H]2CC([C@@H](/C=C([C@H]([C@H](C([C@@H](C[C@@H](/C=C/C=C/C=C([C@@H](OC)C[C@@H]3CC[C@H]([C@@](O3)(C(C(N4CCCC[C@H]4C(O2)=O)=O)=O)O)C)\C)C)C)=O)OC)O)\C)C)=O)C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. eter Armstrong Thompson, et al. Antibody conjugates of immune-modulatory compounds and uses thereof. WO2018227018A1. 2018.

[2]. Peter Armstrong Thompson, et al. Antibody conjugates of immune-modulatory compounds and uses thereof. WO2018227018A1. 2018

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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