1 Result for "

(S)-TNG260

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "(S)-TNG260" in MCE Product Catalog:

Cat. No.: HY-153358A
CAS No.: 2935964-93-3
Purity:  98.84%
Target:  

HDAC

Research Areas:  

Cancer

(S)-TNG260 is an isomer of TNG260 (HY-153358). TNG260 is a CoREST selective deacetylase (CoreDAC) inhibitor. TNG260 inhibits HDAC1 with 10-fold selectivity over HDAC3. TNG260 causes HDAC1 inhibition and reverses anti-PD1 resistance driven by STK11 deletion. TNG260 reduces intratumoral infiltration of neutrophils. TNG260 exhibits immune-mediated cell killing.
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