2 Results for "

σ1 Receptor ligand 1

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "σ1 Receptor ligand 1" in MCE Product Catalog:

Cat. No.: HY-168562
Target:  

Sigma Receptor

Research Areas:  

Neurological Disease Cancer

σ1 Receptor ligand 1 (compound 5I) is a σ1 receptor ligand with a Ki of 3.9 nM. σ1 Receptor ligand 1 has a high plasma protein binding (89%) and promising metabolic stability in the presence of mouse liver microsomes and NADPH. σ1 Receptor ligand 1 can be utilized in neurological and cancer research .
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Cat. No.: HY-181649
CAS No.: 401501-66-4
Target:  

Sigma Receptor

Research Areas:  

Neurological Disease

S1R agonist 3 is a potent, selective and brain-penetrant sigma-1 receptor (S1R) agonist with a Ki of 1.5 nM. S1R agonist 3 reduces hyperlocomotion in wfs1abKO zebrafish larvae without affecting locomotion in wildtype wfs1abWT zebrafish larvae. S1R agonist 3 reverses Aβ25-35 (HY-P0128)-induced learning and memory impairments. S1R ligand 1 can be used for the research of Alzheimer’s disease .
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