4 Results for "

N-terminal truncation

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "N-terminal truncation" in MCE Product Catalog:

  • Targets Recommended:
Cat. No.: HY-P4882
CAS No.: 183449-57-2
Target:  

Amyloid-β Tau Protein

Research Areas:  

Neurological Disease

(Pyr3)-Amyloid β-Protein (3-42) is an N-terminally truncated pyroglutamylated β-amyloid peptide. (Pyr3)-Amyloid β-Protein (3-42) forms stable β-sheet structures across different pH values, co-oligomerizes with Aβ1-42 to form cytotoxic oligomers, induces tau-dependent cytotoxicity and neuronal loss, inhibits hippocampal LTP, and exhibits stronger protease resistance. (Pyr3)-Amyloid β-Protein (3-42) exists in the brain tissues of human Alzheimer's disease patients, correlates with the pathogenesis of Alzheimer's disease, and follows a unique, faster oligomerization pathway. (Pyr3)-Amyloid β-Protein (3-42) can be used in Alzheimer's disease-related research .
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Cat. No.: HY-W198345
CAS No.: 115201-28-0
Target:  

Dipeptidyl Peptidase

Research Areas:  

Metabolic Disease

Val-Pyrrolidide hydrochloride (compound 9) is a DPIV inhibitor. Val-Pyrrolidide hydrochloride can prevent N-terminal truncation of the peptide Gln3-Aβ(1–11) [1] .
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Cat. No.: HY-173467
Target:  

PROTACs c-Myc

Research Areas:  

Cancer

MTP3 is a MYC PROTAC Degrator. MTP3 facilitates ternary complex formation with CRBN, driving proteasome-dependent full-length MYC degradation and partially proteasome-independent N-terminal truncated MYC (tMYC) generation. MTP3 induces tMYC formation across multiple cancer cell lines with context-dependent response variability. MTP3 can be used for the research of prostate cancer, breast cancer .
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Cat. No.: HY-P1459
Target:  

Bacterial

Research Areas:  

Infection

Sphistin Synthetic Peptide (12-38, Fitc in N-Terminal-Fluorescently Labeled Peptide) is a truncated fragments of Sphistin Synthetic Peptide that shows potent antimicrobial activity.
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