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Cat. No.: HY-173467

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MTP3

MTP3 is a PROTAC based MYC degrader (Red: MYC inhibitor (HY-173469), black: linker (HY-W008296), Blue: E3 ligase ligand (HY-14658)).
(Pink: c-Myc ligand (HY-173469); Blue: Cereblon ligand (HY-14658); Black: linker (HY-W008296)).

For research use only. We do not sell to patients.

Formula: C₄₄H₃₈N₆O₈
Molecular Weight:778.81

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

MTP3 Chemical Structure

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

MTP3 is a PROTAC based MYC degrader (Red: MYC inhibitor (HY-173469), black: linker (HY-W008296), Blue: E3 ligase ligand (HY-14658))^[1]. (Pink: c-Myc ligand (HY-173469); Blue: Cereblon ligand (HY-14658); Black: linker (HY-W008296)).

All PROTACs Isoforms :

Chemical Information

Molecular Weight 778.81
Formula C₄₄H₃₈N₆O₈
SMILES

N#CC(C=C1)=CC=C1C2=CC(C3=CC=C(C(NCCCCCCNC(COC4=C(C(N(C5C(NC(CC5)=O)=O)C6=O)=O)C6=CC=C4)=O)=O)C=C3)=CC(C7=CC=CO7)=N2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Boyd SR, et al. MYC-Targeting PROTACs Lead to Bimodal Degradation and N-Terminal Truncation. ACS Chem Biol. 2025 Apr 18;20(4):896-906. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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Biological Activity
- Description
Chemical Information
Purity & Documentation
References

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MTP3

All PROTACs Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

MTP3 Related Classifications

HY-173467 Related Classifications