Val-Pyrrolidide hydrochloride

Cat. No.: HY-W198345 Purity: 99.52%: Data Sheet
COA

SDS
Handling Instructions
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Val-Pyrrolidide hydrochloride (compound 9) is a DPIV inhibitor. Val-Pyrrolidide hydrochloride can prevent N-terminal truncation of the peptide Gln3-Aβ(1–11)^{[1]^.}

For research use only. We do not sell to patients.

Val-Pyrrolidide hydrochloride Chemical Structure

CAS No. : 115201-28-0

Size	Stock	Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	In-stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	In-stock	Estimated Time of Arrival: December 31
Solid
10 mg	In-stock	Estimated Time of Arrival: December 31
25 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	In-stock	Estimated Time of Arrival: December 31
100 mg	In-stock	Estimated Time of Arrival: December 31
200 mg	Get quote
500 mg	Get quote

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Customer Review

Based on 1 publication(s) in Google Scholar

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DPP-1 DPP-2 DPP-4 DPP-8 DPP-9

Biological Activity
Purity & Documentation
References
Customer Review

Description

Val-Pyrrolidide hydrochloride (compound 9) is a DPIV inhibitor. Val-Pyrrolidide hydrochloride can prevent N-terminal truncation of the peptide Gln3-Aβ(1–11)^{[1]^.}

Molecular Weight

206.71

Formula

C₉H₁₉ClN₂O

CAS No.

115201-28-0

Appearance

Solid

Color

White to off-white

SMILES

CC(C)[C@H](N)C(N1CCCC1)=O.Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Store at room temperature, keep dry and cool

In solvent	-80°C	1 year
	-20°C	6 months

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (483.77 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	4.8377 mL	24.1885 mL	48.3769 mL
5 mM	0.9675 mL	4.8377 mL	9.6754 mL
10 mM	0.4838 mL	2.4188 mL	4.8377 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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In Vivo Dissolution Calculator

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Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.52%

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Data Sheet (271 KB) SDS (394 KB)

COA (251 KB) HNMR (257 KB) LCMS (330 KB)

Handling Instructions (2659 KB)

References

[1]. Schilling S, et al. Glutaminyl cyclases unfold glutamyl cyclase activity under mild acid conditions. FEBS Lett. 2004 Apr 9;563(1-3):191-6. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	4.8377 mL	24.1885 mL	48.3770 mL	120.9424 mL
	5 mM	0.9675 mL	4.8377 mL	9.6754 mL	24.1885 mL
	10 mM	0.4838 mL	2.4188 mL	4.8377 mL	12.0942 mL
	15 mM	0.3225 mL	1.6126 mL	3.2251 mL	8.0628 mL
	20 mM	0.2419 mL	1.2094 mL	2.4188 mL	6.0471 mL
	25 mM	0.1935 mL	0.9675 mL	1.9351 mL	4.8377 mL
	30 mM	0.1613 mL	0.8063 mL	1.6126 mL	4.0314 mL
	40 mM	0.1209 mL	0.6047 mL	1.2094 mL	3.0236 mL
	50 mM	0.0968 mL	0.4838 mL	0.9675 mL	2.4188 mL
	60 mM	0.0806 mL	0.4031 mL	0.8063 mL	2.0157 mL
	80 mM	0.0605 mL	0.3024 mL	0.6047 mL	1.5118 mL
	100 mM	0.0484 mL	0.2419 mL	0.4838 mL	1.2094 mL