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Results for "

RO5190591

" in MedChemExpress (MCE) Product Catalog:
製品番号 製品名 Target 研究分野 構造式
  • HY-10238
    Danoprevir
    15+ Cited Publications

    ITMN-191; R7227; RO5190591; RG7227

    		 HCV Protease HCV SARS-CoV Infection
    Danoprevir (ITMN-191) is an orally active NS3/4A protease inhibitor for hepatitis C virus (HCV) with an IC50 of 0.29 nM and is selective for NS3/4A over a panel of 53 proteases (IC50 higher than 10 μM). Danoprevir (ITMN-191) inhibits HCV genotypes 1a, 1b, 4, 5, and 6 (IC50s=0.2-0.4 nM) as well as 2b and 3a (IC50s=1.6, 3.5 nM) . Danoprevir is also a SARS-CoV 3CL pro inhibitor with an IC50 of 0.05 μM .
    Danoprevir
  • HY-10239
    Danoprevir sodium

    ITMN-191 sodium; R7227 sodium; RO5190591 sodium

    		 HCV Others
    Danoprevir (sodium) (ITMN-191) is a compound used to inhibit hepatitis C virus infection.
    Danoprevir sodium
  • HY-10238R
    Danoprevir (Standard)

    ITMN-191 (Standard); R7227 (Standard); RO5190591 (Standard); RG7227 (Standard)

    		 Reference Standards HCV Protease HCV SARS-CoV Infection
    Danoprevir (Standard) is the analytical standard of Danoprevir (HY-10238). This product is intended for research and analytical applications. Danoprevir (ITMN-191) is an orally active NS3/4A protease inhibitor for hepatitis C virus (HCV) with an IC50 of 0.29 nM and is selective for NS3/4A over a panel of 53 proteases (IC50 higher than 10 μM). Danoprevir (ITMN-191) inhibits HCV genotypes 1a, 1b, 4, 5, and 6 (IC50s=0.2-0.4 nM) as well as 2b and 3a (IC50s=1.6, 3.5 nM) . Danoprevir is also a SARS-CoV 3CLpro inhibitor with an IC50 of 0.05 μM .
    Danoprevir (Standard)

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