1 Result for "

1375078-57-1

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "1375078-57-1" in MCE Product Catalog:

Cat. No.: HY-115625
CAS No.: 1375078-57-1
Research Areas:  

Cancer

AG-205 is a progesterone receptor membrane component 1 (PGRMC1) antagonist and CGT inhibitor, with an IC50 of 50 μM against rat CGT. AG-205 exhibits antimitotic, antimigratory and anti-invasive activities. AG-205 increases the expression of genes encoding cholesterol biosynthesis pathway or steroidogenic enzymes. AG-205 promotes the regulation of cell cycle by apoptosis and reduces the migratory and invasive capacities of ovarian and breast cancer cells. AG-205 can be used in research related to renal cancer and breast cancer .
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