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1383814-68-3

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "1383814-68-3" in MCE Product Catalog:

Cat. No.: HY-14879E
CAS No.: 1383814-68-3
Synonyms: ent-NXL-104; ent-AVE1330A
Research Areas:  

Infection Inflammation/Immunology

Ent-Avibactam (NXL-104) sodium is a β-lactamase inhibitor with broad-spectrum antibacterial activity. When combined with Cefazidime (HY-B0593), rel-Avibactam sodium exhibits significant inhibitory effects on Enterobacteriaceae bacteria that produce Ambler A and C types of β-lactamases. The IC50 value of rel-Avibactam sodium is much lower than that of commonly used β-lactamase inhibitors Clavulanic acid (HY-A0256) and Ticarcillin (HY-139805), demonstrating its high efficiency in inhibiting TEM-1 and P99 enzymes .
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