1 Result for "

1430067-36-9

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "1430067-36-9" in MCE Product Catalog:

Cat. No.: HY-115529
CAS No.: 1430067-36-9
Target:  

Bcl-2 Family Apoptosis

Research Areas:  

Cancer

(-)BI97D6 is a broad-spectrum inhibitor of the Bcl-2 protein family, inhibiting Mcl-1, Bcl-2, Bcl-xL and Bcl-1 with IC50 values ​​of 0.025, 0.031, 0.076 and 0.122 μM, respectively. (-)BI97D6 stimulates cell death through the Bak and Bax mediated mitochondrial apoptosis pathway. In addition, (-)BI97D6 inhibits Mcl-1 and can effectively induce apoptosis in acute myeloid leukemia (AML) cells .
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