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1532593-30-8

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "1532593-30-8" in MCE Product Catalog:

8
8 Cited Publications
Cat. No.: HY-12341
CAS No.: 1532593-30-8
Purity:  98.11%
Synonyms: ML355
Onvoloxastat (ML355) is an orally active selective 12-LOX inhibitor with an IC50 of 0.34 μM. Onvoloxastat inhibits platelet activation by blocking thrombin- or thromboxane A2-induced phosphorylation of Akt, PI3K and Erk1/2. At low doses (1-20 μM), it mainly acts by reducing ROS levels, while at high doses (50 μM), it functions via activating the cAMP pathway. Onvoloxastat can be used in research related to thrombosis and diabetes .
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