1 Result for "

153537-73-6

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "153537-73-6" in MCE Product Catalog:

Cat. No.: HY-13728
CAS No.: 153537-73-6
Purity:  98.00%
Synonyms: ZD 9331; BGC9331
Target:  

Thymidylate Synthase

Research Areas:  

Cancer

Plevitrexed (ZD 9331; BGC 9331) is an orally active and potent thymidylate synthase (TS) inhibitor with a Ki of 0.44 nM. Plevitrexed is taken up via the α-folate receptor as well as the reduced folate carrier. Plevitrexed is used for gastric cancer in clinical . Plevitrexed is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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