1 Result for "

1574321-31-5

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "1574321-31-5" in MCE Product Catalog:

Cat. No.: HY-170438
CAS No.: 1574321-31-5
Target:  

EGFR

Research Areas:  

Cancer

EGFR-IN-139 (compound PD 18) is an epidermal growth factor receptor (EGFR) inhibitor, with IC50s of 12.88 (wild type), 10.84 (L858R/T790M), 42.68 (L858R/T790M/C797S) nM, respectively. EGFR-IN-139 displays strong anticancer activity against A549 and H1975 cancer cell lines, which are highly expressed EGFR. EGFR-IN-139 has a strong selectivity to cancer cells. EGFR-IN-139 can be used for nonsmall cell lung cancer (NSCLC) research[1].
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